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Schrodinger
SDGR

217 hedge funds and large institutions have $1.31B invested in Schrodinger in 2025 Q1 according to their latest regulatory filings, with 30 funds opening new positions, 75 increasing their positions, 69 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

206% more call options, than puts

Call options by funds: $15.3M | Put options by funds: $5M

36% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 22

9% more capital invested

Capital invested by funds: $1.19B → $1.31B (+$113M)

6.4% more ownership

Funds ownership: 97.2% → 103.6% (+6.4%)

3% more funds holding

Funds holding: 211 → 217 (+6)

9% more repeat investments, than reductions

Existing positions increased: 75 | Existing positions reduced: 69

Holders
217
Holders Change
+6
Holders Change %
+2.84%
% of All Funds
2.91%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
30
Increased
75
Reduced
69
Closed
22
Calls
$15.3M
Puts
$5M
Net Calls
+$10.3M
Net Calls Change
+$6.94M

Top Buyers

Rank Fund Capital Flow
1
UBS AM
UBS AM
Illinois
+$61.6M
2
CCM
Cadian Capital Management
New York
+$24.9M
3
American Century Companies
American Century Companies
Missouri
+$22.6M
4
Citadel Advisors
Citadel Advisors
Florida
+$11.9M
5
SIMG
Stephens Investment Management Group
Texas
+$8.15M

Top Sellers

Rank Fund Capital Flow
1
Morgan Stanley
Morgan Stanley
New York
-$8.3M
2
PM
Prosight Management
Texas
-$7.55M
3
BlackRock
BlackRock
New York
-$7.5M
4
Millennium Management
Millennium Management
New York
-$5.9M
5
RCMNY
Rubric Capital Management (New York)
New York
-$4.5M
Name Holding Trade Value Shares
Change 		Change in
Stake
JP Morgan Chase
51
JP Morgan Chase
New York
$2.1M -$432K -19,212 -15%
AG
52
Algert Global
California
$1.81M – – –
MAM
53
Monaco Asset Management
Monaco
$1.63M +$56.2K +2,500 +3%
AllianceBernstein
54
AllianceBernstein
Tennessee
$1.55M – – –
SSA
55
Schonfeld Strategic Advisors
New York
$1.53M +$1.21M +53,565 +224%
Susquehanna International Group
56
Susquehanna International Group
Pennsylvania
$1.52M +$257K +11,403 +17%
Barclays
57
Barclays
United Kingdom
$1.51M -$618K -27,460 -26%
Canada Life
58
Canada Life
Manitoba, Canada
$1.36M -$87.5K -3,888 -5%
P8IP
59
Pier 88 Investment Partners
California
$1.33M -$161K -7,160 -10%
Tudor Investment Corp
60
Tudor Investment Corp
Connecticut
$1.22M +$1.13M +50,392 +435%
CCM
61
CloudAlpha Capital Management
Hong Kong
$1.2M +$1.37M +61,000 New
Commonwealth Equity Services
62
Commonwealth Equity Services
Massachusetts
$1.17M +$2.86K +127 +0.2%
UOC
63
UBS O'Connor
Illinois
$1.17M +$273K +12,129 +26%
California State Teachers Retirement System (CalSTRS)
64
California State Teachers Retirement System (CalSTRS)
California
$1.16M – – –
Prudential Financial
65
Prudential Financial
New Jersey
$1.07M -$53.8K -2,390 -4%
Wells Fargo
66
Wells Fargo
California
$1.05M +$351K +15,600 +42%
WG
67
Winton Group
United Kingdom
$1.03M +$1.18M +52,240 New
IIM
68
INTECH Investment Management
Florida
$964K +$473K +21,029 +76%
N
69
Natixis
France
$933K -$970K -43,100 -48%
T. Rowe Price Associates
70
T. Rowe Price Associates
Maryland
$922K +$105K +4,656 +11%
New York State Teachers Retirement System (NYSTRS)
71
New York State Teachers Retirement System (NYSTRS)
New York
$906K -$4.5K -200 -0.4%
Norges Bank
72
Norges Bank
Norway
$888K -$791K -35,149 -44%
Deutsche Bank
73
Deutsche Bank
Germany
$875K -$4.25M -188,717 -81%
State of Wisconsin Investment Board
74
State of Wisconsin Investment Board
Wisconsin
$870K +$12.6K +558 +1%
LPL Financial
75
LPL Financial
California
$804K -$13.4K -597 -1%
1 2
3
4 5

SDGR Hedge Fund Activity: Q1 2025 in Review

217 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Schrodinger (SDGR) for Q1 2025, worth a combined $1.31B — up 9.5% from $1.19B a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new SDGR positions and 22 closed out — a net gain of 8 holders — while 75 added to existing stakes and 69 trimmed.

The largest buyer was UBS AM, adding an estimated $61.6M. The largest seller was Morgan Stanley, cutting an estimated $8.3M.

  • 217 institutional investors held Schrodinger (SDGR) as of Q1 2025, up from 211 in Q4 2024.
  • Funds reported $1.31B of Schrodinger stock for Q1 2025, up 9.5% quarter-over-quarter.
  • 30 funds opened new Schrodinger positions in Q1 2025 and 22 closed out, a net change of +8 holders.
  • The largest Schrodinger buyer in Q1 2025 was UBS AM, an estimated $61.6M added.
  • The largest Schrodinger seller in Q1 2025 was Morgan Stanley, an estimated $8.3M sold.

Based on aggregated 13F filings for Q1 2025.