We are live on ! Find out more
SDGR icon

Schrodinger

221 hedge funds and large institutions have $1.24B invested in Schrodinger in 2025 Q4 according to their latest regulatory filings, with 27 funds opening new positions, 76 increasing their positions, 79 reducing their positions, and 30 closing their positions.

New
Increased
Maintained
Reduced
Closed

425% more call options, than puts

Call options by funds: $41.5M | Put options by funds: $7.89M

0.16% less ownership

Funds ownership: 108.01%107.85% (-0.16%)

4% less repeat investments, than reductions

Existing positions increased: 76 | Existing positions reduced: 79

1% less funds holding

Funds holding: 224221 (-3)

10% less first-time investments, than exits

New positions opened: 27 | Existing positions closed: 30

11% less capital invested

Capital invested by funds: $1.4B → $1.24B (-$152M)

Holders
221
Holders Change
-3
Holders Change %
-1.34%
% of All Funds
2.69%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
27
Increased
76
Reduced
79
Closed
30
Calls
$41.5M
Puts
$7.89M
Net Calls
+$33.6M
Net Calls Change
+$4.09M
Name Holding Trade Value Shares
Change
Change in
Stake
Two Sigma Investments
26
Two Sigma Investments
New York
$7.81M -$6.72M -354,272 -45%
Bank of New York Mellon
27
Bank of New York Mellon
New York
$5.55M -$544K -28,707 -8%
PHP
28
Parkman Healthcare Partners
Connecticut
$5.35M -$782K -41,248 -12%
Connor, Clark & Lunn Investment Management (CC&L)
29
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$4.89M +$3.52M +185,632 +212%
FAM
30
Fred Alger Management
New York
$4.82M +$3.16M +166,706 +162%
Principal Financial Group
31
Principal Financial Group
Iowa
$4.8M -$52.6K -2,775 -1%
Allianz Asset Management
32
Allianz Asset Management
Germany
$4.44M +$4.7M +248,053 New
JAM
33
Jupiter Asset Management
United Kingdom
$4M -$203K -10,733 -5%
AG
34
Algert Global
California
$3.78M +$3.37M +177,537 +524%
PA
35
Perceptive Advisors
New York
$3.62M +$3.84M +202,400 New
Public Sector Pension Investment Board (PSP Investments)
36
Public Sector Pension Investment Board (PSP Investments)
Quebec, Canada
$3.47M -$462K -24,374 -11%
Invesco
37
Invesco
Georgia
$3.41M +$195K +10,307 +6%
Citadel Advisors
38
Citadel Advisors
Florida
$3.36M -$1.87M -98,436 -34%
Allspring Global Investments
39
Allspring Global Investments
North Carolina
$3.31M -$272K -14,363 -7%
HF
40
HRT Financial
New York
$2.94M +$2.24M +118,157 +255%
AQR Capital Management
41
AQR Capital Management
Connecticut
$2.89M +$2.39M +126,303 +357%
SPS
42
Susquehanna Portfolio Strategies
Pennsylvania
$2.83M +$2.46M +129,877 +459%
TAM
43
Tocqueville Asset Management
New York
$2.81M -$289K -15,250 -9%
RhumbLine Advisers
44
RhumbLine Advisers
Massachusetts
$2.76M -$218K -11,479 -7%
Fidelity Investments
45
Fidelity Investments
Massachusetts
$2.71M -$881K -46,445 -23%
Legal & General Group
46
Legal & General Group
United Kingdom
$2.64M -$170K -8,980 -6%
First Trust Advisors
47
First Trust Advisors
Illinois
$2.45M -$502K -26,501 -16%
TI
48
Trexquant Investment
Connecticut
$2.41M +$2.56M +135,024 New
SC
49
Slow Capital
California
$2.35M +$709K +37,374 +40%
Bank of America
50
Bank of America
North Carolina
$2.34M -$1.28M -67,753 -34%