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Schrodinger
SDGR

232 hedge funds and large institutions have $1.43B invested in Schrodinger in 2025 Q2 according to their latest regulatory filings, with 44 funds opening new positions, 79 increasing their positions, 77 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

507% more call options, than puts

Call options by funds: $34.7M | Put options by funds: $5.72M

63% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 27

9% more capital invested

Capital invested by funds: $1.31B → $1.43B (+$120M)

7% more funds holding

Funds holding: 217 → 232 (+15)

6.8% more ownership

Funds ownership: 103.6% → 110.4% (+6.8%)

3% more repeat investments, than reductions

Existing positions increased: 79 | Existing positions reduced: 77

Holders
232
Holders Change
+15
Holders Change %
+6.91%
% of All Funds
3.05%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
44
Increased
79
Reduced
77
Closed
27
Calls
$34.7M
Puts
$5.72M
Net Calls
+$29M
Net Calls Change
+$18.8M

Top Buyers

Rank Fund Capital Flow
1
CCM
Cadian Capital Management
New York
+$44.3M
2
BlackRock
BlackRock
New York
+$30M
3
FCM
Farallon Capital Management
California
+$25.3M
4
UBS Group
UBS Group
Switzerland
+$21.2M
5
Two Sigma Advisers
Two Sigma Advisers
New York
+$13.6M

Top Sellers

Rank Fund Capital Flow
1
UBS AM
UBS AM
Illinois
-$21.5M
2
TAM
Tocqueville Asset Management
New York
-$16.7M
3
Massachusetts Financial Services
Massachusetts Financial Services
Massachusetts
-$13.7M
4
Citadel Advisors
Citadel Advisors
Florida
-$8.49M
5
Millennium Management
Millennium Management
New York
-$8.39M
Name Holding Trade Value Shares
Change 		Change in
Stake
Charles Schwab
26
Charles Schwab
California
$10.5M +$233K +10,202 +2%
Fidelity Investments
27
Fidelity Investments
Massachusetts
$8.79M -$2.02M -88,487 -17%
Royal Bank of Canada
28
Royal Bank of Canada
Ontario, Canada
$7.98M +$8.25M +361,267 +1,026%
TAM
29
Tocqueville Asset Management
New York
$7.88M -$16.7M -732,600 -65%
Bank of New York Mellon
30
Bank of New York Mellon
New York
$7.16M -$1.04M -45,606 -11%
Goldman Sachs
31
Goldman Sachs
New York
$6.45M -$2.08M -90,993 -22%
Principal Financial Group
32
Principal Financial Group
Iowa
$5.58M +$10.5K +462 +0.2%
Citadel Advisors
33
Citadel Advisors
Florida
$5.35M -$8.49M -371,690 -58%
Allspring Global Investments
34
Allspring Global Investments
North Carolina
$4.13M +$707K +30,948 +18%
Universal-Beteiligungs- und Servicegesellschaft
35
Universal-Beteiligungs- und Servicegesellschaft
Germany
$4.1M – – –
Public Sector Pension Investment Board (PSP Investments)
36
Public Sector Pension Investment Board (PSP Investments)
Quebec, Canada
$3.83M +$335K +14,671 +8%
RhumbLine Advisers
37
RhumbLine Advisers
Massachusetts
$3.45M +$302K +13,221 +8%
Envestnet Asset Management
38
Envestnet Asset Management
Illinois
$3.42M -$925K -40,529 -19%
TC
39
Tejara Capital
United Kingdom
$3.27M +$647K +28,322 +21%
Legal & General Group
40
Legal & General Group
United Kingdom
$3.25M +$53.7K +2,354 +1%
Invesco
41
Invesco
Georgia
$3.14M +$480K +21,039 +16%
SSA
42
Schonfeld Strategic Advisors
New York
$3.03M +$1.67M +73,326 +95%
Barclays
43
Barclays
United Kingdom
$2.85M +$1.49M +65,214 +85%
Jane Street
44
Jane Street
New York
$2.82M +$167K +7,310 +6%
Millennium Management
45
Millennium Management
New York
$2.66M -$8.39M -367,367 -74%
N
46
Nuveen
North Carolina
$2.62M -$348K -15,251 -10%
Qube Research & Technologies (QRT)
47
Qube Research & Technologies (QRT)
United Kingdom
$2.55M +$2.9M +126,823 New
IAN
48
Integrated Advisors Network
Texas
$2.47M +$118K +5,178 +4%
Swiss National Bank
49
Swiss National Bank
Switzerland
$2.45M -$29.7K -1,300 -1%
AG
50
Algert Global
California
$2.4M +$628K +27,486 +30%
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SDGR Hedge Fund Activity: Q2 2025 in Review

232 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Schrodinger (SDGR) for Q2 2025, worth a combined $1.43B — up 9.2% from $1.31B a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new SDGR positions and 27 closed out — a net gain of 17 holders — while 79 added to existing stakes and 77 trimmed.

The largest buyer was Cadian Capital Management, adding an estimated $44.3M. The largest seller was UBS AM, cutting an estimated $21.5M.

  • 232 institutional investors held Schrodinger (SDGR) as of Q2 2025, up from 217 in Q1 2025.
  • Funds reported $1.43B of Schrodinger stock for Q2 2025, up 9.2% quarter-over-quarter.
  • 44 funds opened new Schrodinger positions in Q2 2025 and 27 closed out, a net change of +17 holders.
  • The largest Schrodinger buyer in Q2 2025 was Cadian Capital Management, an estimated $44.3M added.
  • The largest Schrodinger seller in Q2 2025 was UBS AM, an estimated $21.5M sold.

Based on aggregated 13F filings for Q2 2025.