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Schrodinger
SDGR

217 hedge funds and large institutions have $1.31B invested in Schrodinger in 2025 Q1 according to their latest regulatory filings, with 30 funds opening new positions, 75 increasing their positions, 69 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

206% more call options, than puts

Call options by funds: $15.3M | Put options by funds: $5M

36% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 22

9% more capital invested

Capital invested by funds: $1.19B → $1.31B (+$113M)

6.4% more ownership

Funds ownership: 97.2% → 103.6% (+6.4%)

3% more funds holding

Funds holding: 211 → 217 (+6)

9% more repeat investments, than reductions

Existing positions increased: 75 | Existing positions reduced: 69

Holders
217
Holders Change
+6
Holders Change %
+2.84%
% of All Funds
2.91%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
30
Increased
75
Reduced
69
Closed
22
Calls
$15.3M
Puts
$5M
Net Calls
+$10.3M
Net Calls Change
+$6.94M

Top Buyers

Rank Fund Capital Flow
1
UBS AM
UBS AM
Illinois
+$61.6M
2
CCM
Cadian Capital Management
New York
+$24.9M
3
American Century Companies
American Century Companies
Missouri
+$22.6M
4
Citadel Advisors
Citadel Advisors
Florida
+$11.9M
5
SIMG
Stephens Investment Management Group
Texas
+$8.15M

Top Sellers

Rank Fund Capital Flow
1
Morgan Stanley
Morgan Stanley
New York
-$8.3M
2
PM
Prosight Management
Texas
-$7.55M
3
BlackRock
BlackRock
New York
-$7.5M
4
Millennium Management
Millennium Management
New York
-$5.9M
5
RCMNY
Rubric Capital Management (New York)
New York
-$4.5M
Name Holding Trade Value Shares
Change 		Change in
Stake
Goldman Sachs
26
Goldman Sachs
New York
$8.12M -$2.33M -103,348 -20%
UBS Group
27
UBS Group
Switzerland
$8.11M +$300K +13,351 +3%
Bank of New York Mellon
28
Bank of New York Mellon
New York
$7.92M -$231K -10,251 -2%
PM
29
Prosight Management
Texas
$7.6M -$7.55M -335,500 -47%
Citigroup
30
Citigroup
New York
$5.67M +$4.43M +196,946 +218%
Principal Financial Group
31
Principal Financial Group
Iowa
$5.46M +$141K +6,266 +2%
Two Sigma Investments
32
Two Sigma Investments
New York
$4.79M +$3.19M +141,930 +141%
Envestnet Asset Management
33
Envestnet Asset Management
Illinois
$4.16M +$560K +24,880 +13%
Universal-Beteiligungs- und Servicegesellschaft
34
Universal-Beteiligungs- und Servicegesellschaft
Germany
$4.03M +$4.59M +204,000 New
SLG
35
Stanley-Laman Group
Pennsylvania
$3.69M +$619K +27,511 +17%
GWM
36
Geneos Wealth Management
Colorado
$3.55M +$2.7M +119,946 +200%
Public Sector Pension Investment Board (PSP Investments)
37
Public Sector Pension Investment Board (PSP Investments)
Quebec, Canada
$3.47M +$836K +37,168 +27%
Allspring Global Investments
38
Allspring Global Investments
North Carolina
$3.44M +$913K +40,568 +30%
Legal & General Group
39
Legal & General Group
United Kingdom
$3.15M -$147K -6,538 -4%
RhumbLine Advisers
40
RhumbLine Advisers
Massachusetts
$3.12M -$11K -488 -0.3%
KCM
41
Kodai Capital Management
Illinois
$3.03M +$3.45M +153,313 New
N
42
Nuveen
North Carolina
$2.87M -$114K -5,088 -3%
Invesco
43
Invesco
Georgia
$2.66M +$84K +3,734 +3%
TC
44
Tejara Capital
United Kingdom
$2.65M +$1.2M +53,265 +66%
Jane Street
45
Jane Street
New York
$2.62M +$1.04M +46,065 +53%
Ameriprise
46
Ameriprise
Minnesota
$2.6M -$142K -6,324 -5%
Two Sigma Advisers
47
Two Sigma Advisers
New York
$2.49M +$2.29M +101,800 +416%
Swiss National Bank
48
Swiss National Bank
Switzerland
$2.43M -$40.5K -1,800 -1%
IAN
49
Integrated Advisors Network
Texas
$2.32M +$6.28K +279 +0.2%
Bank of America
50
Bank of America
North Carolina
$2.27M +$687K +30,538 +36%
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SDGR Hedge Fund Activity: Q1 2025 in Review

217 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Schrodinger (SDGR) for Q1 2025, worth a combined $1.31B — up 9.5% from $1.19B a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new SDGR positions and 22 closed out — a net gain of 8 holders — while 75 added to existing stakes and 69 trimmed.

The largest buyer was UBS AM, adding an estimated $61.6M. The largest seller was Morgan Stanley, cutting an estimated $8.3M.

  • 217 institutional investors held Schrodinger (SDGR) as of Q1 2025, up from 211 in Q4 2024.
  • Funds reported $1.31B of Schrodinger stock for Q1 2025, up 9.5% quarter-over-quarter.
  • 30 funds opened new Schrodinger positions in Q1 2025 and 22 closed out, a net change of +8 holders.
  • The largest Schrodinger buyer in Q1 2025 was UBS AM, an estimated $61.6M added.
  • The largest Schrodinger seller in Q1 2025 was Morgan Stanley, an estimated $8.3M sold.

Based on aggregated 13F filings for Q1 2025.