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Schrodinger

227 hedge funds and large institutions have $748M invested in Schrodinger in 2026 Q1 according to their latest regulatory filings, with 51 funds opening new positions, 80 increasing their positions, 57 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

40% more repeat investments, than reductions

Existing positions increased: 80 | Existing positions reduced: 57

24% more first-time investments, than exits

New positions opened: 51 | Existing positions closed: 41

3% more funds holding

Funds holding: 221227 (+6)

7% less call options, than puts

Call options by funds: $6.38M | Put options by funds: $6.87M

6.02% less ownership

Funds ownership: 107.85%101.83% (-6%)

40% less capital invested

Capital invested by funds: $1.24B → $748M (-$495M)

Holders
227
Holders Change
+6
Holders Change %
+2.71%
% of All Funds
2.79%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
% of All Funds
0.01%
New
51
Increased
80
Reduced
57
Closed
41
Calls
$6.38M
Puts
$6.87M
Net Calls
-$496K
Net Calls Change
-$34.1M
Name Holding Trade Value Shares
Change
Change in
Stake
Millennium Management
26
Millennium Management
New York
$4.74M -$7.76M -561,336 -57%
VFT
27
Vanguard Fiduciary Trust
Pennsylvania
$4.51M +$5.49M +397,409 New
TC
28
Tejara Capital
United Kingdom
$4.42M +$3.69M +267,105 +219%
Connor, Clark & Lunn Investment Management (CC&L)
29
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$3.53M +$518K +37,474 +14%
Bank of New York Mellon
30
Bank of New York Mellon
New York
$3.43M -$119K -8,621 -3%
JP Morgan Chase
31
JP Morgan Chase
New York
$3.13M +$2.81M +203,181 +255%
Principal Financial Group
32
Principal Financial Group
Iowa
$3.12M +$84.3K +6,098 +2%
Qube Research & Technologies (QRT)
33
Qube Research & Technologies (QRT)
United Kingdom
$2.8M +$2.69M +194,717 +374%
Zurich Cantonal Bank
34
Zurich Cantonal Bank
Switzerland
$2.51M +$3.06M +221,321 New
Lazard Asset Management
35
Lazard Asset Management
New York
$2.41M -$26.6M -1,922,483 -90%
Invesco
36
Invesco
Georgia
$2.37M +$251K +18,176 +10%
ECM
37
ExodusPoint Capital Management
New York
$2.31M +$1.95M +140,966 +226%
Public Sector Pension Investment Board (PSP Investments)
38
Public Sector Pension Investment Board (PSP Investments)
Quebec, Canada
$2.28M +$89.6K +6,481 +3%
SPS
39
Susquehanna Portfolio Strategies
Pennsylvania
$2.26M +$564K +40,802 +26%
GCP
40
GSA Capital Partners
United Kingdom
$2.25M +$2.37M +171,358 +640%
Citadel Advisors
41
Citadel Advisors
Florida
$2.24M +$129K +9,332 +5%
JF
42
Jump Financial
Illinois
$2.06M +$2.51M +181,284 New
First Trust Advisors
43
First Trust Advisors
Illinois
$2M +$546K +39,493 +29%
QCM
44
Quantinno Capital Management
New York
$1.98M +$2.41M +174,095 New
JAM
45
Jupiter Asset Management
United Kingdom
$1.95M -$722K -52,204 -23%
RhumbLine Advisers
46
RhumbLine Advisers
Massachusetts
$1.81M +$69.6K +5,037 +3%
Two Sigma Investments
47
Two Sigma Investments
New York
$1.77M -$3.88M -280,892 -64%
Bank of America
48
Bank of America
North Carolina
$1.66M +$207K +14,970 +11%
EC
49
EntryPoint Capital
New York
$1.57M +$1.3M +94,254 +213%
Legal & General Group
50
Legal & General Group
United Kingdom
$1.55M -$154K -11,165 -8%

SDGR Hedge Fund Activity: Q1 2026 in Review

227 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Schrodinger (SDGR) for Q1 2026, worth a combined $748M — down 40% from $1.24B a quarter earlier.

Buyers outnumbered sellers: 51 funds opened new SDGR positions and 41 closed out — a net gain of 10 holders — while 80 added to existing stakes and 57 trimmed.

The largest buyer was Rubric Capital Management (New York), adding an estimated $25.3M. The largest seller was Stephens Investment Management Group, exiting entirely with an estimated $40.2M sold.

  • 227 institutional investors held Schrodinger (SDGR) as of Q1 2026, up from 221 in Q4 2025.
  • Funds reported $748M of Schrodinger stock for Q1 2026, down 40% quarter-over-quarter.
  • 51 funds opened new Schrodinger positions in Q1 2026 and 41 closed out, a net change of +10 holders.
  • The largest Schrodinger buyer in Q1 2026 was Rubric Capital Management (New York), an estimated $25.3M added.
  • The largest Schrodinger seller in Q1 2026 was Stephens Investment Management Group, an estimated $40.2M sold.

Based on aggregated 13F filings for Q1 2026.