Rezolute
RZLT
121 hedge funds and large institutions have $213M invested in Rezolute in 2025 Q4 according to their latest regulatory filings, with 40 funds opening new positions, 45 increasing their positions, 24 reducing their positions, and 34 closing their positions.
147% more call options, than puts
Call options by funds: $4.56M | Put options by funds: $1.84M
88% more repeat investments, than reductions
Existing positions increased: 45 | Existing positions reduced: 24
18% more first-time investments, than exits
New positions opened: 40 | Existing positions closed: 34
4% more funds holding
Funds holding: 116 → 121 (+5)
1.68% more ownership
Funds ownership: 95.72% → 97.39% (+1.7%)
74% less capital invested
Capital invested by funds: $817M → $213M (-$604M)
100% less funds holding in top 10
Funds holding in top 10: 5 → 0 (-5)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
RCM
RA Capital Management
Boston,
Massachusetts
|
+$72M |
| 2 |
OM
Opaleye Management
Boston,
Massachusetts
|
+$42.2M |
| 3 |
Bank of America
Charlotte,
North Carolina
|
+$23.8M |
| 4 |
Balyasny Asset Management
Chicago,
Illinois
|
+$21M |
| 5 |
Federated Hermes
Pittsburgh,
Pennsylvania
|
+$19.6M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Fidelity Investments
Boston,
Massachusetts
|
-$82M |
| 2 |
SL
Siren LLC
Greenwich,
Connecticut
|
-$45.8M |
| 3 |
Blackstone Inc
New York
|
-$28.4M |
| 4 |
MP
Mangrove Partners
Greenwich,
Connecticut
|
-$27.1M |
| 5 |
Marshall Wace
London,
United Kingdom
|
-$25.6M |
RZLT Hedge Fund Activity: Q4 2025 in Review
121 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Rezolute (RZLT) for Q4 2025, worth a combined $213M — down 74% from $817M a quarter earlier.
Buyers outnumbered sellers: 40 funds opened new RZLT positions and 34 closed out — a net gain of 6 holders — while 45 added to existing stakes and 24 trimmed.
The largest buyer was RA Capital Management, opening a new position worth an estimated $72M. The largest seller was Fidelity Investments, cutting an estimated $82M.
- 121 institutional investors held Rezolute (RZLT) as of Q4 2025, up from 116 in Q3 2025.
- Funds reported $213M of Rezolute stock for Q4 2025, down 74% quarter-over-quarter.
- 40 funds opened new Rezolute positions in Q4 2025 and 34 closed out, a net change of +6 holders.
- The largest Rezolute buyer in Q4 2025 was RA Capital Management, an estimated $72M added.
- The largest Rezolute seller in Q4 2025 was Fidelity Investments, an estimated $82M sold.
Based on aggregated 13F filings for Q4 2025.