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Rezolute

116 hedge funds and large institutions have $817M invested in Rezolute in 2025 Q3 according to their latest regulatory filings, with 35 funds opening new positions, 40 increasing their positions, 28 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,373% more call options, than puts

Call options by funds: $10.4M | Put options by funds: $706K

218% more first-time investments, than exits

New positions opened: 35 | Existing positions closed: 11

135% more capital invested

Capital invested by funds: $347M → $817M (+$470M)

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

43% more repeat investments, than reductions

Existing positions increased: 40 | Existing positions reduced: 28

26% more funds holding

Funds holding: 92116 (+24)

4.61% more ownership

Funds ownership: 91.11%95.72% (+4.6%)

Holders
116
Holders Change
+24
Holders Change %
+26.09%
% of All Funds
1.52%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.07%
New
35
Increased
40
Reduced
28
Closed
11
Calls
$10.4M
Puts
$706K
Net Calls
+$9.7M
Net Calls Change
+$6.47M
Name Holding Trade Value Shares
Change
Change in
Stake
Federated Hermes
1
Federated Hermes
Pennsylvania
$132M
Fidelity Investments
2
Fidelity Investments
Massachusetts
$120M -$317K -47,643 -0.4%
BlackRock
3
BlackRock
New York
$47M +$6.15M +922,911 +23%
SL
4
Siren LLC
Connecticut
$45.8M +$32.4M +4,870,000 New
Vanguard Group
5
Vanguard Group
Pennsylvania
$41.5M +$2.58M +387,502 +10%
Blackstone Inc
6
Blackstone Inc
New York
$28.4M -$3.57M -536,390 -15%
MP
7
Mangrove Partners
Connecticut
$27.1M +$3.89M +584,660 +25%
Marshall Wace
8
Marshall Wace
United Kingdom
$25.6M -$1.05M -158,166 -5%
UBS Group
9
UBS Group
Switzerland
$25.3M -$2.27M -341,190 -11%
GPP
10
Great Point Partners
Connecticut
$23M -$3.87M -581,653 -19%
VC
11
Vivo Capital
California
$19.9M
AAA
12
Affinity Asset Advisors
New York
$19.7M -$666K -100,000 -5%
State Street
13
State Street
Massachusetts
$19.7M +$8.4M +1,261,402 +152%
IHAM
14
Integral Health Asset Management
New York
$18.8M +$1.33M +200,000 +11%
CC
15
Caxton Corporation
New Jersey
$18.7M +$2.55M +382,832 +24%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$17.4M +$908K +136,341 +8%
Balyasny Asset Management
17
Balyasny Asset Management
Illinois
$17.1M +$12.1M +1,822,728 New
RA
18
Rosalind Advisors
Ontario, Canada
$17M +$439K +65,991 +4%
Bank of America
19
Bank of America
North Carolina
$12.1M +$8.05M +1,208,408 +1,579%
Point72 Asset Management
20
Point72 Asset Management
Connecticut
$10.9M +$6.3M +945,901 +447%
WP
21
Woodline Partners
California
$8.83M -$6.43M -965,287 -51%
SC
22
Stempoint Capital
New York
$8.63M +$1.82M +272,976 +42%
OM
23
Opaleye Management
Massachusetts
$8.49M
2L
24
22NW LP
Washington
$7.71M +$5.46M +820,653 New
ACM
25
ADAR1 Capital Management
Texas
$7.67M -$1.15M -173,322 -18%

RZLT Hedge Fund Activity: Q3 2025 in Review

116 of the 7,625 institutional investors tracked by Wall St. Rank reported a position in Rezolute (RZLT) for Q3 2025, worth a combined $817M — up 135% from $347M a quarter earlier.

Buyers outnumbered sellers: 35 funds opened new RZLT positions and 11 closed out — a net gain of 24 holders — while 40 added to existing stakes and 28 trimmed.

The largest buyer was Siren LLC, opening a new position worth an estimated $32.4M. The largest seller was Nantahala Capital Management, exiting entirely with an estimated $10.2M sold.

  • 116 institutional investors held Rezolute (RZLT) as of Q3 2025, up from 92 in Q2 2025.
  • Funds reported $817M of Rezolute stock for Q3 2025, up 135% quarter-over-quarter.
  • 35 funds opened new Rezolute positions in Q3 2025 and 11 closed out, a net change of +24 holders.
  • The largest Rezolute buyer in Q3 2025 was Siren LLC, an estimated $32.4M added.
  • The largest Rezolute seller in Q3 2025 was Nantahala Capital Management, an estimated $10.2M sold.

Based on aggregated 13F filings for Q3 2025.