Rezolute
RZLT
116 hedge funds and large institutions have $817M invested in Rezolute in 2025 Q3 according to their latest regulatory filings, with 35 funds opening new positions, 40 increasing their positions, 28 reducing their positions, and 11 closing their positions.
1,373% more call options, than puts
Call options by funds: $10.4M | Put options by funds: $706K
218% more first-time investments, than exits
New positions opened: 35 | Existing positions closed: 11
135% more capital invested
Capital invested by funds: $347M → $817M (+$470M)
67% more funds holding in top 10
Funds holding in top 10: 3 → 5 (+2)
43% more repeat investments, than reductions
Existing positions increased: 40 | Existing positions reduced: 28
26% more funds holding
Funds holding: 92 → 116 (+24)
4.61% more ownership
Funds ownership: 91.11% → 95.72% (+4.6%)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
SL
Siren LLC
Greenwich,
Connecticut
|
+$32.4M |
| 2 |
Balyasny Asset Management
Chicago,
Illinois
|
+$12.1M |
| 3 |
State Street
Boston,
Massachusetts
|
+$8.4M |
| 4 |
Bank of America
Charlotte,
North Carolina
|
+$8.05M |
| 5 |
Point72 Asset Management
Stamford,
Connecticut
|
+$6.3M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
NCM
Nantahala Capital Management
New Canaan,
Connecticut
|
-$10.2M |
| 2 |
CP
Caligan Partners
New York
|
-$6.88M |
| 3 |
WP
Woodline Partners
San Francisco,
California
|
-$6.43M |
| 4 |
GPP
Great Point Partners
Greenwich,
Connecticut
|
-$3.87M |
| 5 |
Blackstone Inc
New York
|
-$3.57M |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
126
Raymond James Financial
St Petersburg,
Florida
| – | -$46.2K | -10,350 | Closed |
|
RZLT Hedge Fund Activity: Q3 2025 in Review
116 of the 7,625 institutional investors tracked by Wall St. Rank reported a position in Rezolute (RZLT) for Q3 2025, worth a combined $817M — up 135% from $347M a quarter earlier.
Buyers outnumbered sellers: 35 funds opened new RZLT positions and 11 closed out — a net gain of 24 holders — while 40 added to existing stakes and 28 trimmed.
The largest buyer was Siren LLC, opening a new position worth an estimated $32.4M. The largest seller was Nantahala Capital Management, exiting entirely with an estimated $10.2M sold.
- 116 institutional investors held Rezolute (RZLT) as of Q3 2025, up from 92 in Q2 2025.
- Funds reported $817M of Rezolute stock for Q3 2025, up 135% quarter-over-quarter.
- 35 funds opened new Rezolute positions in Q3 2025 and 11 closed out, a net change of +24 holders.
- The largest Rezolute buyer in Q3 2025 was Siren LLC, an estimated $32.4M added.
- The largest Rezolute seller in Q3 2025 was Nantahala Capital Management, an estimated $10.2M sold.
Based on aggregated 13F filings for Q3 2025.