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Relay Therapeutics

199 hedge funds and large institutions have $867M invested in Relay Therapeutics in 2025 Q3 according to their latest regulatory filings, with 20 funds opening new positions, 63 increasing their positions, 63 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

2,019% more call options, than puts

Call options by funds: $3.98M | Put options by funds: $188K

47% more capital invested

Capital invested by funds: $592M → $867M (+$276M)

0% more funds holding in top 10

Funds holding in top 10: 55 (0)

0% more repeat investments, than reductions

Existing positions increased: 63 | Existing positions reduced: 63

3.34% less ownership

Funds ownership: 99.71%96.38% (-3.3%)

4% less funds holding

Funds holding: 208199 (-9)

23% less first-time investments, than exits

New positions opened: 20 | Existing positions closed: 26

Holders
199
Holders Change
-9
Holders Change %
-4.33%
% of All Funds
2.61%
Holding in Top 10
5
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.07%
New
20
Increased
63
Reduced
63
Closed
26
Calls
$3.98M
Puts
$188K
Net Calls
+$3.79M
Net Calls Change
+$3.92M
Name Holding Trade Value Shares
Change
Change in
Stake
SAM
176
Smartleaf Asset Management
Massachusetts
$5.91K +$3.9K +1,023 +882%
SS
177
SBI Securities
Japan
$5.25K -$4 -1 -0.1%
WB
178
Webster Bank
Connecticut
$5.22K
UB
179
UMB Bank
Missouri
$3.84K +$2.8K +735 New
RTL
180
Red Tortoise LLC
Georgia
$3.64K
Comerica Bank
181
Comerica Bank
Texas
$3.47K
IA
182
IFP Advisors
Florida
$3.01K +$1.55K +407 +241%
Daiwa Securities Group
183
Daiwa Securities Group
Japan
$3K
VCM
184
Versant Capital Management
Arizona
$2.57K
RIL
185
Rothschild Investment LLC
Illinois
$2.4K -$286 -75 -14%
CA
186
Clearstead Advisors
Ohio
$1.58K +$1.11K +290 +2,231%
FFO
187
Fortitude Family Office
Arizona
$1.57K +$553 +145 +93%
TWD
188
True Wealth Design
Ohio
$1.45K +$622 +163 +142%
HFS
189
Hughes Financial Services
Virginia
$1.39K
MCM
190
MAI Capital Management
Ohio
$945
Jones Financial Companies
191
Jones Financial Companies
Missouri
$796
GRP
192
Global Retirement Partners
California
$679
PFBT
193
Parkside Financial Bank & Trust
Missouri
$674 +$492 +129 New
YAL
194
Your Advocates Ltd
Texas
$522
ASN
195
Advisory Services Network
Georgia
$423 +$309 +81 New
SS
196
Sunbelt Securities
Texas
$271 +$198 +52 New
TFA
197
Transamerica Financial Advisors
Florida
$68 +$50 +13 New
Norges Bank
198
Norges Bank
Norway
-$2.89M -835,874 Closed
Ameriprise
199
Ameriprise
Minnesota
-$1.42M -410,896 Closed
HP
200
Harbourvest Partners
Massachusetts
-$1.03M -296,402 Closed

RLAY Hedge Fund Activity: Q3 2025 in Review

199 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Relay Therapeutics (RLAY) for Q3 2025, worth a combined $867M — up 47% from $592M a quarter earlier.

Sellers outnumbered buyers: 26 funds closed out of RLAY and 20 opened new positions — a net loss of 6 holders — while 63 trimmed existing stakes and 63 added.

The largest buyer was Commodore Capital, adding an estimated $13.9M. The largest seller was JP Morgan Chase, cutting an estimated $14.8M.

  • 199 institutional investors held Relay Therapeutics (RLAY) as of Q3 2025, down from 208 in Q2 2025.
  • Funds reported $867M of Relay Therapeutics stock for Q3 2025, up 47% quarter-over-quarter.
  • 20 funds opened new Relay Therapeutics positions in Q3 2025 and 26 closed out, a net change of -6 holders.
  • The largest Relay Therapeutics buyer in Q3 2025 was Commodore Capital, an estimated $13.9M added.
  • The largest Relay Therapeutics seller in Q3 2025 was JP Morgan Chase, an estimated $14.8M sold.

Based on aggregated 13F filings for Q3 2025.