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Relay Therapeutics

199 hedge funds and large institutions have $867M invested in Relay Therapeutics in 2025 Q3 according to their latest regulatory filings, with 20 funds opening new positions, 63 increasing their positions, 63 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

2,019% more call options, than puts

Call options by funds: $3.98M | Put options by funds: $188K

47% more capital invested

Capital invested by funds: $592M → $867M (+$276M)

0% more funds holding in top 10

Funds holding in top 10: 55 (0)

0% more repeat investments, than reductions

Existing positions increased: 63 | Existing positions reduced: 63

3.34% less ownership

Funds ownership: 99.71%96.38% (-3.3%)

4% less funds holding

Funds holding: 208199 (-9)

23% less first-time investments, than exits

New positions opened: 20 | Existing positions closed: 26

Holders
199
Holders Change
-9
Holders Change %
-4.33%
% of All Funds
2.61%
Holding in Top 10
5
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.07%
New
20
Increased
63
Reduced
63
Closed
26
Calls
$3.98M
Puts
$188K
Net Calls
+$3.79M
Net Calls Change
+$3.92M
Name Holding Trade Value Shares
Change
Change in
Stake
DP
101
Diadema Partners
New Jersey
$228K
LPL Financial
102
LPL Financial
California
$219K +$65.2K +17,100 +69%
IIM
103
INTECH Investment Management
Florida
$202K -$59.2K -15,534 -29%
BM
104
Brandywine Managers
Delaware
$201K
CAM
105
Cresset Asset Management
Illinois
$194K
PFSRSONJ
106
Police & Firemen's Retirement System of New Jersey
New Jersey
$193K +$17.7K +4,632 +14%
Janus Henderson Group
107
Janus Henderson Group
United Kingdom
$193K
Federated Hermes
108
Federated Hermes
Pennsylvania
$188K -$134K -35,217 -49%
Blackstone Inc
109
Blackstone Inc
New York
$186K
ASRS
110
Arizona State Retirement System
Arizona
$185K +$3.37K +884 +3%
DS
111
DRW Securities
Illinois
$177K +$18.9K +4,956 +17%
PA
112
Profund Advisors
Maryland
$176K -$18.8K -4,923 -13%
VIA
113
Virtus Investment Advisers
Connecticut
$172K +$21.8K +5,726 +21%
BNP Paribas Financial Markets
114
BNP Paribas Financial Markets
France
$168K -$12.2K -3,199 -9%
SG Americas Securities
115
SG Americas Securities
New York
$167K +$18.4K +4,825 +18%
CUAMC
116
China Universal Asset Management Company
China
$158K -$16.1K -4,213 -12%
QOP
117
Quinn Opportunity Partners
Virginia
$157K +$76.3K +20,000 +200%
New York State Common Retirement Fund
118
New York State Common Retirement Fund
New York
$153K
Teacher Retirement System of Texas
119
Teacher Retirement System of Texas
Texas
$151K -$11.8K -3,083 -10%
ProShare Advisors
120
ProShare Advisors
Maryland
$150K -$18.2K -4,781 -14%
FT
121
Fiduciary Trust
Massachusetts
$146K
VPIM
122
Vanguard Personalized Indexing Management
California
$145K +$7.93K +2,079 +8%
Mariner
123
Mariner
Kansas
$145K +$53.7K +14,094 +103%
State Board of Administration of Florida Retirement System
124
State Board of Administration of Florida Retirement System
Florida
$135K
SEI Investments
125
SEI Investments
Pennsylvania
$134K

RLAY Hedge Fund Activity: Q3 2025 in Review

199 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Relay Therapeutics (RLAY) for Q3 2025, worth a combined $867M — up 47% from $592M a quarter earlier.

Sellers outnumbered buyers: 26 funds closed out of RLAY and 20 opened new positions — a net loss of 6 holders — while 63 trimmed existing stakes and 63 added.

The largest buyer was Commodore Capital, adding an estimated $13.9M. The largest seller was JP Morgan Chase, cutting an estimated $14.8M.

  • 199 institutional investors held Relay Therapeutics (RLAY) as of Q3 2025, down from 208 in Q2 2025.
  • Funds reported $867M of Relay Therapeutics stock for Q3 2025, up 47% quarter-over-quarter.
  • 20 funds opened new Relay Therapeutics positions in Q3 2025 and 26 closed out, a net change of -6 holders.
  • The largest Relay Therapeutics buyer in Q3 2025 was Commodore Capital, an estimated $13.9M added.
  • The largest Relay Therapeutics seller in Q3 2025 was JP Morgan Chase, an estimated $14.8M sold.

Based on aggregated 13F filings for Q3 2025.