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Relay Therapeutics

208 hedge funds and large institutions have $592M invested in Relay Therapeutics in 2025 Q2 according to their latest regulatory filings, with 36 funds opening new positions, 73 increasing their positions, 55 reducing their positions, and 34 closing their positions.

New
Increased
Maintained
Reduced
Closed

35% more capital invested

Capital invested by funds: $439M → $592M (+$153M)

33% more repeat investments, than reductions

Existing positions increased: 73 | Existing positions reduced: 55

25% more funds holding in top 10

Funds holding in top 10: 45 (+1)

1.03% more ownership

Funds ownership: 98.69%99.71% (+1%)

6% more first-time investments, than exits

New positions opened: 36 | Existing positions closed: 34

0% more funds holding

Funds holding: 207208 (+1)

99% less call options, than puts

Call options by funds: $1K | Put options by funds: $128K

Holders
208
Holders Change
+1
Holders Change %
+0.48%
% of All Funds
2.74%
Holding in Top 10
5
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+25%
% of All Funds
0.07%
New
36
Increased
73
Reduced
55
Closed
34
Calls
$1K
Puts
$128K
Net Calls
-$127K
Net Calls Change
-$481K
Name Holding Trade Value Shares
Change
Change in
Stake
IIM
101
INTECH Investment Management
Florida
$188K -$80.9K -27,185 -33%
PP
102
PDT Partners
New York
$186K
Marshall Wace
103
Marshall Wace
United Kingdom
$179K +$154K +51,698 New
TI
104
TrueMark Investments
Illinois
$172K -$5.67K -1,908 -4%
EC
105
EntryPoint Capital
New York
$162K -$73K -24,527 -34%
DP
106
Diadema Partners
New Jersey
$151K -$1.14M -382,730 -90%
Wealth Enhancement Advisory Services
107
Wealth Enhancement Advisory Services
Minnesota
$149K +$75.9K +25,511 +165%
JG
108
Jain Global
New York
$138K -$11.8K -3,965 -9%
EGM
109
Engineers Gate Manager
New York
$134K +$27.6K +9,281 +32%
PA
110
Profund Advisors
Maryland
$134K -$12.8K -4,306 -10%
BM
111
Brandywine Managers
Delaware
$133K
CAM
112
Cresset Asset Management
Illinois
$128K +$22.9K +7,705 +26%
Janus Henderson Group
113
Janus Henderson Group
United Kingdom
$128K
VOYA Investment Management
114
VOYA Investment Management
Georgia
$126K +$6.93K +2,331 +7%
Blackstone Inc
115
Blackstone Inc
New York
$123K
BNP Paribas Financial Markets
116
BNP Paribas Financial Markets
France
$123K +$50.1K +16,851 +91%
PCM
117
Polymer Capital Management
New York
$121K -$102K -34,415 -50%
ASRS
118
Arizona State Retirement System
Arizona
$120K +$3.03K +1,020 +3%
CUAMC
119
China Universal Asset Management Company
China
$119K +$1.28K +431 +1%
ProShare Advisors
120
ProShare Advisors
Maryland
$116K -$3.94K -1,325 -4%
PFSRSONJ
121
Police & Firemen's Retirement System of New Jersey
New Jersey
$112K +$26.7K +8,973 +38%
Teacher Retirement System of Texas
122
Teacher Retirement System of Texas
Texas
$111K +$1.35K +454 +1%
DS
123
DRW Securities
Illinois
$103K +$56.2K +18,886 +176%
New York State Common Retirement Fund
124
New York State Common Retirement Fund
New York
$102K
Zurich Cantonal Bank
125
Zurich Cantonal Bank
Switzerland
$99.3K

RLAY Hedge Fund Activity: Q2 2025 in Review

208 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Relay Therapeutics (RLAY) for Q2 2025, worth a combined $592M — up 35% from $439M a quarter earlier.

Buyers outnumbered sellers: 36 funds opened new RLAY positions and 34 closed out — a net gain of 2 holders — while 73 added to existing stakes and 55 trimmed.

The largest buyer was Commodore Capital, opening a new position worth an estimated $39.7M. The largest seller was Norges Bank, cutting an estimated $11.3M.

  • 208 institutional investors held Relay Therapeutics (RLAY) as of Q2 2025, up from 207 in Q1 2025.
  • Funds reported $592M of Relay Therapeutics stock for Q2 2025, up 35% quarter-over-quarter.
  • 36 funds opened new Relay Therapeutics positions in Q2 2025 and 34 closed out, a net change of +2 holders.
  • The largest Relay Therapeutics buyer in Q2 2025 was Commodore Capital, an estimated $39.7M added.
  • The largest Relay Therapeutics seller in Q2 2025 was Norges Bank, an estimated $11.3M sold.

Based on aggregated 13F filings for Q2 2025.