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Relay Therapeutics

199 hedge funds and large institutions have $867M invested in Relay Therapeutics in 2025 Q3 according to their latest regulatory filings, with 20 funds opening new positions, 63 increasing their positions, 63 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

2,019% more call options, than puts

Call options by funds: $3.98M | Put options by funds: $188K

47% more capital invested

Capital invested by funds: $592M → $867M (+$276M)

0% more funds holding in top 10

Funds holding in top 10: 55 (0)

0% more repeat investments, than reductions

Existing positions increased: 63 | Existing positions reduced: 63

3.34% less ownership

Funds ownership: 99.71%96.38% (-3.3%)

4% less funds holding

Funds holding: 208199 (-9)

23% less first-time investments, than exits

New positions opened: 20 | Existing positions closed: 26

Holders
199
Holders Change
-9
Holders Change %
-4.33%
% of All Funds
2.61%
Holding in Top 10
5
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.07%
New
20
Increased
63
Reduced
63
Closed
26
Calls
$3.98M
Puts
$188K
Net Calls
+$3.79M
Net Calls Change
+$3.92M
Name Holding Trade Value Shares
Change
Change in
Stake
Royal Bank of Canada
51
Royal Bank of Canada
Ontario, Canada
$1.15M -$829K -217,479 -50%
RBI
52
Raiffeisen Bank International
Austria
$1.14M +$153K +40,000 +22%
RhumbLine Advisers
53
RhumbLine Advisers
Massachusetts
$1.14M -$16.2K -4,261 -2%
Raymond James Financial
54
Raymond James Financial
Florida
$1.12M +$92.8K +24,335 +13%
UBS AM
55
UBS AM
Illinois
$1.06M -$788K -206,658 -51%
HF
56
HRT Financial
New York
$1.03M +$700K +183,589 +1,300%
IC
57
IEQ Capital
California
$1.03M +$65.3K +17,135 +10%
Man Group
58
Man Group
United Kingdom
$980K -$422K -110,689 -37%
Osaic Holdings
59
Osaic Holdings
Arizona
$970K +$703K +184,475 +9,643%
Jane Street
60
Jane Street
New York
$965K +$705K +184,951 New
Fidelity Investments
61
Fidelity Investments
Massachusetts
$850K +$17.4K +4,563 +3%
Manulife (Manufacturers Life Insurance)
62
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$848K -$189K -49,661 -23%
UBS Group
63
UBS Group
Switzerland
$795K -$79.5K -20,837 -12%
Rafferty Asset Management
64
Rafferty Asset Management
New York
$791K -$116K -30,382 -17%
AllianceBernstein
65
AllianceBernstein
Tennessee
$758K
California State Teachers Retirement System (CalSTRS)
66
California State Teachers Retirement System (CalSTRS)
California
$723K +$123K +32,264 +30%
BFM
67
Boothbay Fund Management
New York
$720K -$325K -85,146 -38%
Susquehanna International Group
68
Susquehanna International Group
Pennsylvania
$715K -$645K -169,180 -55%
GCP
69
GSA Capital Partners
United Kingdom
$676K +$186K +48,860 +61%
SFI
70
Susquehanna Fundamental Investments
Pennsylvania
$628K -$606K -158,940 -57%
Deutsche Bank
71
Deutsche Bank
Germany
$627K +$39.7K +10,404 +9%
TD Asset Management
72
TD Asset Management
Ontario, Canada
$617K +$73.2K +19,200 +19%
Legal & General Group
73
Legal & General Group
United Kingdom
$586K
Wells Fargo
74
Wells Fargo
California
$530K +$63.1K +16,560 +19%
DekaBank Deutsche Girozentrale
75
DekaBank Deutsche Girozentrale
Germany
$527K

RLAY Hedge Fund Activity: Q3 2025 in Review

199 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Relay Therapeutics (RLAY) for Q3 2025, worth a combined $867M — up 47% from $592M a quarter earlier.

Sellers outnumbered buyers: 26 funds closed out of RLAY and 20 opened new positions — a net loss of 6 holders — while 63 trimmed existing stakes and 63 added.

The largest buyer was Commodore Capital, adding an estimated $13.9M. The largest seller was JP Morgan Chase, cutting an estimated $14.8M.

  • 199 institutional investors held Relay Therapeutics (RLAY) as of Q3 2025, down from 208 in Q2 2025.
  • Funds reported $867M of Relay Therapeutics stock for Q3 2025, up 47% quarter-over-quarter.
  • 20 funds opened new Relay Therapeutics positions in Q3 2025 and 26 closed out, a net change of -6 holders.
  • The largest Relay Therapeutics buyer in Q3 2025 was Commodore Capital, an estimated $13.9M added.
  • The largest Relay Therapeutics seller in Q3 2025 was JP Morgan Chase, an estimated $14.8M sold.

Based on aggregated 13F filings for Q3 2025.