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Relay Therapeutics

207 hedge funds and large institutions have $439M invested in Relay Therapeutics in 2025 Q1 according to their latest regulatory filings, with 34 funds opening new positions, 73 increasing their positions, 60 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

274% more call options, than puts

Call options by funds: $483K | Put options by funds: $129K

42% more first-time investments, than exits

New positions opened: 34 | Existing positions closed: 24

22% more repeat investments, than reductions

Existing positions increased: 73 | Existing positions reduced: 60

4% more funds holding

Funds holding: 199207 (+8)

0.73% more ownership

Funds ownership: 97.95%98.69% (+0.73%)

33% less funds holding in top 10

Funds holding in top 10: 64 (-2)

35% less capital invested

Capital invested by funds: $676M → $439M (-$237M)

Holders
207
Holders Change
+8
Holders Change %
+4.02%
% of All Funds
2.78%
Holding in Top 10
4
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-33.33%
% of All Funds
0.05%
New
34
Increased
73
Reduced
60
Closed
24
Calls
$483K
Puts
$129K
Net Calls
+$354K
Net Calls Change
-$140K
Name Holding Trade Value Shares
Change
Change in
Stake
Citadel Advisors
51
Citadel Advisors
Florida
$884K -$1.37M -349,610 -51%
Bank of New York Mellon
52
Bank of New York Mellon
New York
$864K +$3.95K +1,008 +0.3%
TI
53
Trexquant Investment
Connecticut
$850K -$2.56M -653,668 -67%
N
54
Nuveen
North Carolina
$839K -$1.3M -333,033 -51%
American Century Companies
55
American Century Companies
Missouri
$809K +$143K +36,586 +13%
UBS AM
56
UBS AM
Illinois
$790K +$270K +68,968 +30%
HP
57
Harbourvest Partners
Massachusetts
$777K
UBS Group
58
UBS Group
Switzerland
$722K -$265K -67,688 -20%
Citigroup
59
Citigroup
New York
$682K +$214K +54,637 +27%
Susquehanna International Group
60
Susquehanna International Group
Pennsylvania
$673K +$707K +180,465 +236%
HighTower Advisors
61
HighTower Advisors
Illinois
$648K +$186K +47,433 +24%
Balyasny Asset Management
62
Balyasny Asset Management
Illinois
$606K -$1.81M -460,837 -67%
Swiss National Bank
63
Swiss National Bank
Switzerland
$595K +$29K +7,400 +3%
BFM
64
Boothbay Fund Management
New York
$594K +$48.3K +12,338 +6%
DekaBank Deutsche Girozentrale
65
DekaBank Deutsche Girozentrale
Germany
$572K +$35K +8,937 +15%
Man Group
66
Man Group
United Kingdom
$539K +$126K +32,116 +18%
Manulife (Manufacturers Life Insurance)
67
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$539K -$52.1K -13,293 -6%
Rafferty Asset Management
68
Rafferty Asset Management
New York
$537K -$174K -44,493 -18%
SSA
69
Schonfeld Strategic Advisors
New York
$535K -$589K -150,445 -42%
PHP
70
Parkman Healthcare Partners
Connecticut
$493K -$1.22M -312,496 -62%
RBI
71
Raiffeisen Bank International
Austria
$490K
CWM
72
Congress Wealth Management
Massachusetts
$487K +$729K +186,063 New
Invesco
73
Invesco
Georgia
$484K +$256K +65,414 +55%
Raymond James Financial
74
Raymond James Financial
Florida
$483K -$17.7K -4,513 -2%
RhumbLine Advisers
75
RhumbLine Advisers
Massachusetts
$456K +$10.5K +2,681 +2%

RLAY Hedge Fund Activity: Q1 2025 in Review

207 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Relay Therapeutics (RLAY) for Q1 2025, worth a combined $439M — down 35% from $676M a quarter earlier.

Buyers outnumbered sellers: 34 funds opened new RLAY positions and 24 closed out — a net gain of 10 holders — while 73 added to existing stakes and 60 trimmed.

The largest buyer was Point72 Asset Management, adding an estimated $36.2M. The largest seller was Vanguard Group, cutting an estimated $11.5M.

  • 207 institutional investors held Relay Therapeutics (RLAY) as of Q1 2025, up from 199 in Q4 2024.
  • Funds reported $439M of Relay Therapeutics stock for Q1 2025, down 35% quarter-over-quarter.
  • 34 funds opened new Relay Therapeutics positions in Q1 2025 and 24 closed out, a net change of +10 holders.
  • The largest Relay Therapeutics buyer in Q1 2025 was Point72 Asset Management, an estimated $36.2M added.
  • The largest Relay Therapeutics seller in Q1 2025 was Vanguard Group, an estimated $11.5M sold.

Based on aggregated 13F filings for Q1 2025.