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Repligen

441 hedge funds and large institutions have $7.76B invested in Repligen in 2026 Q1 according to their latest regulatory filings, with 67 funds opening new positions, 165 increasing their positions, 131 reducing their positions, and 91 closing their positions.

New
Increased
Maintained
Reduced
Closed

26% more repeat investments, than reductions

Existing positions increased: 165 | Existing positions reduced: 131

5.38% more ownership

Funds ownership: 110.91%116.29% (+5.4%)

7% less funds holding

Funds holding: 473441 (-32)

24% less capital invested

Capital invested by funds: $10.2B → $7.76B (-$2.48B)

25% less funds holding in top 10

Funds holding in top 10: 86 (-2)

26% less first-time investments, than exits

New positions opened: 67 | Existing positions closed: 91

46% less call options, than puts

Call options by funds: $24.5M | Put options by funds: $45.7M

Holders
441
Holders Change
-32
Holders Change %
-6.77%
% of All Funds
5.43%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.07%
New
67
Increased
165
Reduced
131
Closed
91
Calls
$24.5M
Puts
$45.7M
Net Calls
-$21.2M
Net Calls Change
+$15.5M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$706M -$87.5M -626,217 -9%
T. Rowe Price Associates
2
T. Rowe Price Associates
Maryland
$575M +$39M +279,080 +6%
Fidelity Investments
3
Fidelity Investments
Massachusetts
$340M +$2.65M +18,940 +0.7%
UCFA
4
United Capital Financial Advisors
Texas
$327M +$436K +3,118 +0.1%
VCM
5
Vanguard Capital Management
Pennsylvania
$282M +$335M +2,396,511 New
VPM
6
Vanguard Portfolio Management
Pennsylvania
$272M +$322M +2,305,094 New
State Street
7
State Street
Massachusetts
$209M +$8.13M +58,192 +3%
Bank of New York Mellon
8
Bank of New York Mellon
New York
$180M +$26.1M +186,696 +14%
MC
9
Maverick Capital
Texas
$179M +$212M +1,518,805 New
Massachusetts Financial Services
10
Massachusetts Financial Services
Massachusetts
$165M +$25.4M +181,988 +15%
T. Rowe Price Investment Management
11
T. Rowe Price Investment Management
Maryland
$161M +$101M +720,558 +112%
Invesco
12
Invesco
Georgia
$151M +$3.05M +21,816 +2%
WA
13
Wasatch Advisors
Utah
$147M +$174M +1,243,531 New
RI
14
RTW Investments
New York
$142M +$19.8M +142,000 +13%
Franklin Resources
15
Franklin Resources
California
$141M +$12.8M +91,692 +8%
AllianceBernstein
16
AllianceBernstein
Tennessee
$136M -$22.8M -163,077 -16%
Citadel Advisors
17
Citadel Advisors
Florida
$130M -$41.2M -295,071 -21%
CCA
18
Conestoga Capital Advisors
Pennsylvania
$129M +$5.56M +39,808 +4%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$125M +$4.84M +34,640 +3%
Ameriprise
20
Ameriprise
Minnesota
$109M +$60.2M +430,989 +87%
VPC
21
Vestal Point Capital
New York
$109M +$118M +842,000 +1,014%
Dimensional Fund Advisors
22
Dimensional Fund Advisors
Texas
$101M +$7.03M +50,331 +6%
CAM
23
Congress Asset Management
Massachusetts
$94M +$7.2M +51,561 +7%
SIMG
24
Stephens Investment Management Group
Texas
$89M +$13.8M +98,460 +15%
Holocene Advisors
25
Holocene Advisors
New York
$83.5M -$35.2M -252,151 -26%

RGEN Hedge Fund Activity: Q1 2026 in Review

441 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Repligen (RGEN) for Q1 2026, worth a combined $7.76B — down 24% from $10.2B a quarter earlier.

Sellers outnumbered buyers: 91 funds closed out of RGEN and 67 opened new positions — a net loss of 24 holders — while 131 trimmed existing stakes and 165 added.

The largest buyer was Maverick Capital, opening a new position worth an estimated $212M. The largest seller was Millennium Management, cutting an estimated $87.7M.

  • 441 institutional investors held Repligen (RGEN) as of Q1 2026, down from 473 in Q4 2025.
  • Funds reported $7.76B of Repligen stock for Q1 2026, down 24% quarter-over-quarter.
  • 67 funds opened new Repligen positions in Q1 2026 and 91 closed out, a net change of -24 holders.
  • The largest Repligen buyer in Q1 2026 was Maverick Capital, an estimated $212M added.
  • The largest Repligen seller in Q1 2026 was Millennium Management, an estimated $87.7M sold.

Based on aggregated 13F filings for Q1 2026.