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Repligen

443 hedge funds and large institutions have $7.22B invested in Repligen in 2025 Q2 according to their latest regulatory filings, with 74 funds opening new positions, 130 increasing their positions, 173 reducing their positions, and 70 closing their positions.

New
Increased
Maintained
Reduced
Closed

1.35% more ownership

Funds ownership: 102.58%103.93% (+1.4%)

6% more first-time investments, than exits

New positions opened: 74 | Existing positions closed: 70

0% more funds holding

Funds holding: 441443 (+2)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

2% less capital invested

Capital invested by funds: $7.37B → $7.22B (-$151M)

25% less repeat investments, than reductions

Existing positions increased: 130 | Existing positions reduced: 173

88% less call options, than puts

Call options by funds: $10.2M | Put options by funds: $84.6M

Holders
443
Holders Change
+2
Holders Change %
+0.45%
% of All Funds
5.83%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
74
Increased
130
Reduced
173
Closed
70
Calls
$10.2M
Puts
$84.6M
Net Calls
-$74.4M
Net Calls Change
-$16.8M
Name Holding Trade Value Shares
Change
Change in
Stake
T. Rowe Price Associates
1
T. Rowe Price Associates
Maryland
$821M -$122M -962,139 -13%
BlackRock
2
BlackRock
New York
$756M -$93.8M -737,257 -11%
Vanguard Group
3
Vanguard Group
Pennsylvania
$631M -$346K -2,722 -0.1%
Point72 Asset Management
4
Point72 Asset Management
Connecticut
$238M +$101M +796,745 +71%
State Street
5
State Street
Massachusetts
$202M -$8.44M -66,314 -4%
Fidelity Investments
6
Fidelity Investments
Massachusetts
$201M +$112M +880,900 +120%
CIP
7
Champlain Investment Partners
Vermont
$174M -$8.01M -62,907 -4%
Invesco
8
Invesco
Georgia
$172M -$37.6M -295,350 -18%
Bank of New York Mellon
9
Bank of New York Mellon
New York
$165M -$3.14M -24,697 -2%
Sands Capital Management
10
Sands Capital Management
Virginia
$156M -$5.49M -43,108 -3%
Citadel Advisors
11
Citadel Advisors
Florida
$132M -$33.9M -266,679 -20%
BCM
12
Brown Capital Management
Maryland
$125M +$18M +141,241 +16%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$122M -$1.38M -10,820 -1%
CCA
14
Conestoga Capital Advisors
Pennsylvania
$122M -$425K -3,340 -0.3%
Holocene Advisors
15
Holocene Advisors
New York
$117M -$2.95M -23,168 -2%
AllianceBernstein
16
AllianceBernstein
Tennessee
$113M -$15M -117,787 -12%
Dimensional Fund Advisors
17
Dimensional Fund Advisors
Texas
$95.5M +$6.92M +54,355 +8%
Impax Asset Management Group
18
Impax Asset Management Group
United Kingdom
$93.8M -$5.53M -43,468 -5%
Millennium Management
19
Millennium Management
New York
$87.2M +$86.7M +681,342 +3,424%
New York State Common Retirement Fund
20
New York State Common Retirement Fund
New York
$75.4M -$2.46M -19,352 -3%
DDC
21
DF Dent & Co
Maryland
$72.9M +$1.5M +11,797 +2%
T. Rowe Price Investment Management
22
T. Rowe Price Investment Management
Maryland
$69.6M +$38M +298,731 +115%
Morgan Stanley
23
Morgan Stanley
New York
$65.8M -$7.03M -55,232 -9%
SIMG
24
Stephens Investment Management Group
Texas
$65M -$2.12M -16,695 -3%
ECM
25
ExodusPoint Capital Management
New York
$61.2M +$35.8M +281,668 +134%

RGEN Hedge Fund Activity: Q2 2025 in Review

443 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Repligen (RGEN) for Q2 2025, worth a combined $7.22B — down 2.1% from $7.37B a quarter earlier.

Buyers outnumbered sellers: 74 funds opened new RGEN positions and 70 closed out — a net gain of 4 holders — while 130 added to existing stakes and 173 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $112M. The largest seller was T. Rowe Price Associates, cutting an estimated $122M.

  • 443 institutional investors held Repligen (RGEN) as of Q2 2025, up from 441 in Q1 2025.
  • Funds reported $7.22B of Repligen stock for Q2 2025, down 2.1% quarter-over-quarter.
  • 74 funds opened new Repligen positions in Q2 2025 and 70 closed out, a net change of +4 holders.
  • The largest Repligen buyer in Q2 2025 was Fidelity Investments, an estimated $112M added.
  • The largest Repligen seller in Q2 2025 was T. Rowe Price Associates, an estimated $122M sold.

Based on aggregated 13F filings for Q2 2025.