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Arcus Biosciences

209 hedge funds and large institutions have $2.89B invested in Arcus Biosciences in 2025 Q4 according to their latest regulatory filings, with 48 funds opening new positions, 95 increasing their positions, 38 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,666% more call options, than puts

Call options by funds: $92.8M | Put options by funds: $5.26M

150% more repeat investments, than reductions

Existing positions increased: 95 | Existing positions reduced: 38

112% more capital invested

Capital invested by funds: $1.37B → $2.89B (+$1.53B)

100% more funds holding in top 10

Funds holding in top 10: 24 (+2)

78% more first-time investments, than exits

New positions opened: 48 | Existing positions closed: 27

17.94% more ownership

Funds ownership: 94.53%112.48% (+18%)

10% more funds holding

Funds holding: 190209 (+19)

Holders
209
Holders Change
+19
Holders Change %
+10%
% of All Funds
2.54%
Holding in Top 10
4
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+100%
% of All Funds
0.05%
New
48
Increased
95
Reduced
38
Closed
27
Calls
$92.8M
Puts
$5.26M
Net Calls
+$87.6M
Net Calls Change
+$43.6M
Name Holding Trade Value Shares
Change
Change in
Stake
GWM
201
Gilpin Wealth Management
Colorado
$263 +$224 +11 New
AW
202
Ankerstar Wealth
Texas
$262 +$224 +11 New
SS
203
SBI Securities
Japan
$95 -$58.4K -2,862 -100%
II
204
Inspire Investing
Idaho
$45 +$41 +2 New
Northwestern Mutual Wealth Management
205
Northwestern Mutual Wealth Management
Wisconsin
$24
TFM
206
TFC Financial Management
Massachusetts
$24
Walleye Capital
207
Walleye Capital
New York
$24 +$20 +1 New
RCM
208
RA Capital Management
Massachusetts
-$15.5M -1,136,364 Closed
Macquarie Group
209
Macquarie Group
Australia
-$5.16M -379,100 Closed
Nordea Investment Management
210
Nordea Investment Management
Sweden
-$4.33M -328,459 Closed
Two Sigma Advisers
211
Two Sigma Advisers
New York
-$3.88M -285,400 Closed
VPC
212
Vestal Point Capital
New York
-$3.4M -250,000 Closed
Arrowstreet Capital
213
Arrowstreet Capital
Massachusetts
-$3.26M -239,420 Closed
Adage Capital Partners
214
Adage Capital Partners
Massachusetts
-$2.07M -152,000 Closed
Group One Trading
215
Group One Trading
Illinois
-$2.66M -130,449 Closed
Simplex Trading
216
Simplex Trading
Illinois
-$2.14M -105,025 Closed
HF
217
HRT Financial
New York
-$1.22M -89,997 Closed
AG
218
Algert Global
California
-$1.13M -82,950 Closed
Man Group
219
Man Group
United Kingdom
-$1.03M -75,486 Closed
AA
220
ALPS Advisors
Colorado
-$716K -52,624 Closed
TI
221
Trexquant Investment
Connecticut
-$647K -47,593 Closed
BHCM
222
Brevan Howard Capital Management
Jersey
-$573K -42,113 Closed
Acadian Asset Management
223
Acadian Asset Management
Massachusetts
-$438K -32,358 Closed
JG
224
Jain Global
New York
-$207K -15,256 Closed
IFU
225
iSAM Funds (UK)
United Kingdom
-$190K -13,959 Closed

RCUS Hedge Fund Activity: Q4 2025 in Review

209 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Arcus Biosciences (RCUS) for Q4 2025, worth a combined $2.89B — up 112% from $1.37B a quarter earlier.

Buyers outnumbered sellers: 48 funds opened new RCUS positions and 27 closed out — a net gain of 21 holders — while 95 added to existing stakes and 38 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $79.9M. The largest seller was Fidelity Investments, cutting an estimated $23.7M.

  • 209 institutional investors held Arcus Biosciences (RCUS) as of Q4 2025, up from 190 in Q3 2025.
  • Funds reported $2.89B of Arcus Biosciences stock for Q4 2025, up 112% quarter-over-quarter.
  • 48 funds opened new Arcus Biosciences positions in Q4 2025 and 27 closed out, a net change of +21 holders.
  • The largest Arcus Biosciences buyer in Q4 2025 was Wellington Management Group, an estimated $79.9M added.
  • The largest Arcus Biosciences seller in Q4 2025 was Fidelity Investments, an estimated $23.7M sold.

Based on aggregated 13F filings for Q4 2025.