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Arcus Biosciences

190 hedge funds and large institutions have $1.37B invested in Arcus Biosciences in 2025 Q3 according to their latest regulatory filings, with 30 funds opening new positions, 65 increasing their positions, 61 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

2,013% more call options, than puts

Call options by funds: $46.2M | Put options by funds: $2.19M

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

69% more capital invested

Capital invested by funds: $811M → $1.37B (+$557M)

25% more first-time investments, than exits

New positions opened: 30 | Existing positions closed: 24

3% more funds holding

Funds holding: 185190 (+5)

7% more repeat investments, than reductions

Existing positions increased: 65 | Existing positions reduced: 61

0.36% more ownership

Funds ownership: 94.18%94.53% (+0.36%)

Holders
190
Holders Change
+5
Holders Change %
+2.7%
% of All Funds
2.49%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
30
Increased
65
Reduced
61
Closed
24
Calls
$46.2M
Puts
$2.19M
Net Calls
+$44M
Net Calls Change
+$19.1M
Name Holding Trade Value Shares
Change
Change in
Stake
DC
26
Decheng Capital
California
$7.45M +$4.03M +387,609 +242%
Two Sigma Investments
27
Two Sigma Investments
New York
$6.41M +$658K +63,327 +16%
Bank of New York Mellon
28
Bank of New York Mellon
New York
$6.39M -$144K -13,843 -3%
GIM
29
Granahan Investment Management
Massachusetts
$6.2M -$364K -35,017 -7%
Susquehanna International Group
30
Susquehanna International Group
Pennsylvania
$5.29M +$423K +40,681 +12%
PP
31
PDT Partners
New York
$5.28M -$9.87K -949 -0.2%
Macquarie Group
32
Macquarie Group
Australia
$5.16M
CS
33
Candriam SCA
Luxembourg
$5.15M +$3.93M +378,441 New
SAM
34
Sectoral Asset Management
Quebec, Canada
$5.01M +$1.15M +110,800 +43%
Hudson Bay Capital Management
35
Hudson Bay Capital Management
Connecticut
$4.62M -$936K -90,000 -21%
Principal Financial Group
36
Principal Financial Group
Iowa
$4.55M -$17.7K -1,701 -0.5%
Aberdeen Group
37
Aberdeen Group
United Kingdom
$4.42M +$3.45M +331,671 New
Nordea Investment Management
38
Nordea Investment Management
Sweden
$4.33M +$89K +8,560 +3%
Citadel Advisors
39
Citadel Advisors
Florida
$4.01M -$3.29M -316,141 -52%
Invesco
40
Invesco
Georgia
$3.98M +$422K +40,553 +16%
Two Sigma Advisers
41
Two Sigma Advisers
New York
$3.88M -$108K -10,400 -4%
Public Sector Pension Investment Board (PSP Investments)
42
Public Sector Pension Investment Board (PSP Investments)
Quebec, Canada
$3.67M +$404K +38,839 +17%
VPC
43
Vestal Point Capital
New York
$3.4M +$2.6M +250,000 New
SPS
44
Susquehanna Portfolio Strategies
Pennsylvania
$3.26M -$83.2K -8,000 -3%
Arrowstreet Capital
45
Arrowstreet Capital
Massachusetts
$3.26M +$2.49M +239,420 New
AIM
46
AXA Investment Managers
France
$3.16M +$2.42M +232,668 New
Jane Street
47
Jane Street
New York
$3.07M -$2.67M -256,457 -53%
Renaissance Technologies
48
Renaissance Technologies
New York
$2.98M -$1.55M -148,800 -40%
Ameriprise
49
Ameriprise
Minnesota
$2.85M +$565K +54,362 +35%
RhumbLine Advisers
50
RhumbLine Advisers
Massachusetts
$2.85M -$7.48K -719 -0.3%

RCUS Hedge Fund Activity: Q3 2025 in Review

190 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Arcus Biosciences (RCUS) for Q3 2025, worth a combined $1.37B — up 69% from $811M a quarter earlier.

Buyers outnumbered sellers: 30 funds opened new RCUS positions and 24 closed out — a net gain of 6 holders — while 65 added to existing stakes and 61 trimmed.

The largest buyer was Siren LLC, adding an estimated $13.5M. The largest seller was Point72 Asset Management, cutting an estimated $17M.

  • 190 institutional investors held Arcus Biosciences (RCUS) as of Q3 2025, up from 185 in Q2 2025.
  • Funds reported $1.37B of Arcus Biosciences stock for Q3 2025, up 69% quarter-over-quarter.
  • 30 funds opened new Arcus Biosciences positions in Q3 2025 and 24 closed out, a net change of +6 holders.
  • The largest Arcus Biosciences buyer in Q3 2025 was Siren LLC, an estimated $13.5M added.
  • The largest Arcus Biosciences seller in Q3 2025 was Point72 Asset Management, an estimated $17M sold.

Based on aggregated 13F filings for Q3 2025.