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Ultragenyx Pharmaceutical

285 hedge funds and large institutions have $2.16B invested in Ultragenyx Pharmaceutical in 2025 Q4 according to their latest regulatory filings, with 56 funds opening new positions, 110 increasing their positions, 91 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less ownership

Funds ownership:

less funds holding

Funds holding:

14% less first-time investments, than exits

New positions opened: 56 | Existing positions closed: 65

25% less capital invested

Capital invested by funds: $2.87B → $2.16B (-$711M)

50% less funds holding in top 10

Funds holding in top 10: 42 (-2)

Holders
285
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$75.9M
Puts
$47.6M
Net Calls
Net Calls Change

Top Buyers

1 +$65.6M
2 +$30.1M
3 +$29.5M
4
Millennium Management
Millennium Management
New York
+$25.7M
5
Jane Street
Jane Street
New York
+$21.9M

Top Sellers

1 -$152M
2 -$31.1M
3 -$29.6M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$24.9M
5
VPC
Vestal Point Capital
New York
-$22.6M
Name Holding Trade Value Shares
Change
Change in
Stake
PHP
126
Parkman Healthcare Partners
Connecticut
$1.43M
BC
127
Birchview Capital
Vermont
$1.43M
FISPB
128
Fideuram - Intesa Sanpaolo Private Banking
$1.41M
ET
129
Entropy Technologies
New York
$1.39M
State of Wisconsin Investment Board
130
State of Wisconsin Investment Board
Wisconsin
$1.35M
Nordea Investment Management
131
Nordea Investment Management
Sweden
$1.32M
PA
132
Profund Advisors
Maryland
$1.3M
FPC
133
Flax Pond Capital
Massachusetts
$1.29M
II
134
Ishara Investments
California
$1.15M
QCM
135
Quantinno Capital Management
New York
$1.14M
GC
136
Guggenheim Capital
Illinois
$1.13M
SRL
137
Scientech Research LLC
New Jersey
$1.1M
WCM
138
Wedge Capital Management
North Carolina
$973K
PFSRSONJ
139
Police & Firemen's Retirement System of New Jersey
New Jersey
$906K
Treasurer of the State of North Carolina
140
Treasurer of the State of North Carolina
North Carolina
$888K
AIMCA
141
Alberta Investment Management Corp (AIMCo)
Alberta, Canada
$883K
Janus Henderson Group
142
Janus Henderson Group
United Kingdom
$840K
Walleye Capital
143
Walleye Capital
New York
$839K
Pathstone Holdings
144
Pathstone Holdings
New Jersey
$790K
New York State Common Retirement Fund
145
New York State Common Retirement Fund
New York
$783K
Handelsbanken Fonder
146
Handelsbanken Fonder
Sweden
$771K
SG Americas Securities
147
SG Americas Securities
New York
$741K
SCM
148
Superstring Capital Management
New York
$730K
Toronto Dominion Bank
149
Toronto Dominion Bank
Ontario, Canada
$729K
State of New Jersey Common Pension Fund D
150
State of New Jersey Common Pension Fund D
New Jersey
$681K