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Ultragenyx Pharmaceutical

299 hedge funds and large institutions have $3.25B invested in Ultragenyx Pharmaceutical in 2025 Q1 according to their latest regulatory filings, with 33 funds opening new positions, 127 increasing their positions, 104 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

40% more funds holding in top 10

Funds holding in top 10: 57 (+2)

22% more repeat investments, than reductions

Existing positions increased: 127 | Existing positions reduced: 104

2.35% more ownership

Funds ownership: 94.76%97.11% (+2.4%)

4% more call options, than puts

Call options by funds: $43.9M | Put options by funds: $42.2M

4% less funds holding

Funds holding: 312299 (-13)

12% less capital invested

Capital invested by funds: $3.68B → $3.25B (-$427M)

25% less first-time investments, than exits

New positions opened: 33 | Existing positions closed: 44

Holders
299
Holders Change
-13
Holders Change %
-4.17%
% of All Funds
4.01%
Holding in Top 10
7
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+40%
% of All Funds
0.09%
New
33
Increased
127
Reduced
104
Closed
44
Calls
$43.9M
Puts
$42.2M
Net Calls
+$1.65M
Net Calls Change
+$8.06M
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$362M -$1.61M -38,636 -0.4%
BlackRock
2
BlackRock
New York
$223M -$15.7M -378,251 -6%
Sands Capital Management
3
Sands Capital Management
Virginia
$151M -$5.59M -134,442 -3%
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$117M +$29.4M +706,519 +28%
State Street
5
State Street
Massachusetts
$94.8M -$4.33M -104,134 -4%
Wellington Management Group
6
Wellington Management Group
Massachusetts
$88.7M -$335K -8,045 -0.3%
ClearBridge Investments
7
ClearBridge Investments
New York
$81.8M -$2.6M -62,500 -3%
Adage Capital Partners
8
Adage Capital Partners
Massachusetts
$77.8M +$40.2M +965,919 +82%
Federated Hermes
9
Federated Hermes
Pennsylvania
$74.4M +$225K +5,400 +0.3%
SCM
10
Suvretta Capital Management
New York
$73.3M +$36.3M +873,186 +76%
RI
11
RTW Investments
New York
$61.8M -$10.8M -260,600 -13%
Deutsche Bank
12
Deutsche Bank
Germany
$61.6M +$349K +8,385 +0.5%
Alkeon Capital Management
13
Alkeon Capital Management
New York
$61M -$41.1K -987 -0.1%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$59.6M +$3.48M +83,747 +5%
BBA
15
Baker Bros. Advisors
New York
$57.1M
Alyeska Investment Group
16
Alyeska Investment Group
Illinois
$54.1M +$2.31M +55,611 +4%
Pictet Asset Management
17
Pictet Asset Management
Switzerland
$52M +$9.8M +235,561 +20%
RSCM
18
Rock Springs Capital Management
Maryland
$50.5M -$14.4M -345,379 -20%
DTC
19
Deep Track Capital
Connecticut
$48.9M +$29M +696,487 +107%
AllianceBernstein
20
AllianceBernstein
Tennessee
$45.2M -$15.8M -380,552 -23%
Invesco
21
Invesco
Georgia
$43.9M -$20.2M -486,474 -29%
BNP Paribas Asset Management
22
BNP Paribas Asset Management
France
$41.7M +$8M +192,379 +20%
Norges Bank
23
Norges Bank
Norway
$35.6M +$909K +21,844 +2%
Point72 Asset Management
24
Point72 Asset Management
Connecticut
$35.3M -$8.6M -206,825 -17%
Two Sigma Advisers
25
Two Sigma Advisers
New York
$33.9M +$986K +23,700 +3%

RARE Hedge Fund Activity: Q1 2025 in Review

299 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Ultragenyx Pharmaceutical (RARE) for Q1 2025, worth a combined $3.25B — down 12% from $3.68B a quarter earlier.

Sellers outnumbered buyers: 44 funds closed out of RARE and 33 opened new positions — a net loss of 11 holders — while 104 trimmed existing stakes and 127 added.

The largest buyer was Adage Capital Partners, adding an estimated $40.2M. The largest seller was Vestal Point Capital, cutting an estimated $41.6M.

  • 299 institutional investors held Ultragenyx Pharmaceutical (RARE) as of Q1 2025, down from 312 in Q4 2024.
  • Funds reported $3.25B of Ultragenyx Pharmaceutical stock for Q1 2025, down 12% quarter-over-quarter.
  • 33 funds opened new Ultragenyx Pharmaceutical positions in Q1 2025 and 44 closed out, a net change of -11 holders.
  • The largest Ultragenyx Pharmaceutical buyer in Q1 2025 was Adage Capital Partners, an estimated $40.2M added.
  • The largest Ultragenyx Pharmaceutical seller in Q1 2025 was Vestal Point Capital, an estimated $41.6M sold.

Based on aggregated 13F filings for Q1 2025.