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Ultragenyx Pharmaceutical
RARE

Overview Fund Activity

297 hedge funds and large institutions have $3.22B invested in Ultragenyx Pharmaceutical in 2025 Q1 according to their latest regulatory filings, with 34 funds opening new positions, 125 increasing their positions, 104 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
297
Holders Change
-13
Holders Change %
-4.19%
% of All Funds
4.03%
Holding in Top 10
7
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+40%
% of All Funds
0.1%
New
34
Increased
125
Reduced
104
Closed
44
Calls
$43.9M
Puts
$42.2M
Net Calls
+$1.65M
Net Calls Change
+$8.06M

Top Buyers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$35M
2
SCM
Suvretta Capital Management
New York
+$31.6M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$25.6M
4
DTC
Deep Track Capital
Connecticut
+$25.2M
5
PCH
Polar Capital Holdings
United Kingdom
+$23.6M

Top Sellers

1
VPC
Vestal Point Capital
New York
-$36.2M
2
Marshall Wace
Marshall Wace
United Kingdom
-$26M
3
First Trust Advisors
First Trust Advisors
Illinois
-$19.1M
4
Invesco
Invesco
Georgia
-$17.6M
5
AllianceBernstein
AllianceBernstein
Tennessee
-$13.8M
Name Holding Trade Value Shares
Change 		Shares
Change %
Vanguard Group
1
Vanguard Group
Pennsylvania
$362M -$1.4M -38,636 -0.4%
BlackRock
2
BlackRock
New York
$223M -$13.7M -378,251 -6%
Sands Capital Management
3
Sands Capital Management
Virginia
$151M -$4.87M -134,442 -3%
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$117M +$25.6M +706,519 +28%
State Street
5
State Street
Massachusetts
$94.8M -$3.77M -104,134 -4%
Wellington Management Group
6
Wellington Management Group
Massachusetts
$88.7M -$291K -8,045 -0.3%
ClearBridge Investments
7
ClearBridge Investments
New York
$81.8M -$2.26M -62,500 -3%
Adage Capital Partners
8
Adage Capital Partners
Massachusetts
$77.8M +$35M +965,919 +82%
Federated Hermes
9
Federated Hermes
Pennsylvania
$74.4M +$196K +5,400 +0.3%
SCM
10
Suvretta Capital Management
New York
$73.3M +$31.6M +873,186 +76%
RI
11
RTW Investments
New York
$61.8M -$9.44M -260,600 -13%
Deutsche Bank
12
Deutsche Bank
Germany
$61.6M +$304K +8,385 +0.5%
Alkeon Capital Management
13
Alkeon Capital Management
New York
$61M -$35.7K -987 -0.1%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$59.6M +$3.03M +83,747 +5%
BBA
15
Baker Bros. Advisors
New York
$57.1M – – –
Alyeska Investment Group
16
Alyeska Investment Group
Illinois
$54.1M +$2.01M +55,611 +4%
Pictet Asset Management
17
Pictet Asset Management
Switzerland
$52M +$8.69M +235,561 +20%
RSCM
18
Rock Springs Capital Management
Maryland
$50.5M -$12.5M -345,379 -20%
DTC
19
Deep Track Capital
Connecticut
$48.9M +$25.2M +696,487 +107%
AllianceBernstein
20
AllianceBernstein
Tennessee
$45.2M -$13.8M -380,552 -23%
Invesco
21
Invesco
Georgia
$43.9M -$17.6M -486,474 -29%
BNP Paribas Asset Management
22
BNP Paribas Asset Management
France
$41.7M +$6.97M +192,379 +20%
Point72 Asset Management
23
Point72 Asset Management
Connecticut
$35.3M -$7.49M -206,825 -17%
Two Sigma Advisers
24
Two Sigma Advisers
New York
$33.9M +$858K +23,700 +3%
DCM
25
Driehaus Capital Management
Illinois
$30.9M +$840K +23,192 +3%
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