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Ultragenyx Pharmaceutical
RARE

Overview Fund Activity

307 hedge funds and large institutions have $3.42B invested in Ultragenyx Pharmaceutical in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 116 increasing their positions, 108 reducing their positions, and 43 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
307
Holders Change
+10
Holders Change %
+3.37%
% of All Funds
4.12%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
54
Increased
116
Reduced
108
Closed
43
Calls
$149M
Puts
$87.7M
Net Calls
+$60.8M
Net Calls Change
+$59.2M

Top Buyers

1
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
$119M
2
Fidelity Investments
Fidelity Investments
Massachusetts
$94.7M
3
BBA
Baker Bros. Advisors
New York
$101M
4
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
$42.3M
5
FCM
Farallon Capital Management
California
$32.7M

Top Sellers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
$55.6M
2
Wellington Management Group
Wellington Management Group
Massachusetts
$68.1M
3
ACA
Avoro Capital Advisors
New York
$12M
4
VPC
Vestal Point Capital
New York
$0
5
Invesco
Invesco
Georgia
$26.3M
Name Holding Trade Value Shares
Change 		Shares
Change %
Vanguard Group
1
Vanguard Group
Pennsylvania
$371M +$7.9M +217,196 +2%
BlackRock
2
BlackRock
New York
$227M +$3.56M +97,879 +2%
Sands Capital Management
3
Sands Capital Management
Virginia
$143M -$8M -220,076 -5%
JPMorgan Chase & Co
4
JPMorgan Chase & Co
New York
$119M +$107M +2,951,397 +954%
T. Rowe Price Associates
5
T. Rowe Price Associates
Maryland
$105M -$12.1M -332,674 -10%
BBA
6
Baker Bros. Advisors
New York
$101M +$43.5M +1,196,578 +76%
Fidelity Investments
7
Fidelity Investments
Massachusetts
$94.7M +$80.8M +2,223,166 +583%
State Street
8
State Street
Massachusetts
$93.5M -$1.68M -46,250 -2%
SCM
9
Suvretta Capital Management
New York
$82.8M +$9.22M +253,500 +13%
ClearBridge Investments
10
ClearBridge Investments
New York
$77.8M -$4.33M -119,128 -5%
Federated Hermes
11
Federated Hermes
Pennsylvania
$74.5M -$207K -5,699 -0.3%
Wellington Management Group
12
Wellington Management Group
Massachusetts
$68.1M -$21M -577,678 -24%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$62.3M +$2.41M +66,394 +4%
RI
14
RTW Investments
New York
$62.1M – – –
Pictet Asset Management
15
Pictet Asset Management
Switzerland
$61.9M +$10.6M +290,745 +21%
Alkeon Capital Management
16
Alkeon Capital Management
New York
$61.3M – – –
Deutsche Bank
17
Deutsche Bank
Germany
$60.6M -$1.3M -35,641 -2%
Adage Capital Partners
18
Adage Capital Partners
Massachusetts
$55.6M -$22.5M -619,526 -29%
BNP Paribas Asset Management
19
BNP Paribas Asset Management
France
$52.8M +$11M +301,674 +26%
Alyeska Investment Group
20
Alyeska Investment Group
Illinois
$52M -$2.4M -65,914 -4%
RSCM
21
Rock Springs Capital Management
Maryland
$50.6M -$122K -3,362 -0.2%
DTC
22
Deep Track Capital
Connecticut
$49.1M – – –
AllianceBernstein
23
AllianceBernstein
Tennessee
$45.6M +$284K +7,823 +0.6%
Assenagon Asset Management
24
Assenagon Asset Management
Luxembourg
$42.3M +$34.5M +947,865 +439%
FLSM
25
Frazier Life Sciences Management
California
$35.8M +$11.8M +325,000 +49%
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