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Ultragenyx Pharmaceutical

285 hedge funds and large institutions have $2.16B invested in Ultragenyx Pharmaceutical in 2025 Q4 according to their latest regulatory filings, with 56 funds opening new positions, 110 increasing their positions, 91 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less ownership

Funds ownership:

less funds holding

Funds holding:

14% less first-time investments, than exits

New positions opened: 56 | Existing positions closed: 65

25% less capital invested

Capital invested by funds: $2.87B → $2.16B (-$711M)

50% less funds holding in top 10

Funds holding in top 10: 42 (-2)

Holders
285
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$75.9M
Puts
$47.6M
Net Calls
Net Calls Change

Top Buyers

1 +$65.6M
2 +$30.1M
3 +$29.5M
4
Millennium Management
Millennium Management
New York
+$25.7M
5
Jane Street
Jane Street
New York
+$21.9M

Top Sellers

1 -$152M
2 -$31.1M
3 -$29.6M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$24.9M
5
VPC
Vestal Point Capital
New York
-$22.6M
Name Holding Trade Value Shares
Change
Change in
Stake
MCM
76
Moore Capital Management
New York
$4.6M
Assenagon Asset Management
77
Assenagon Asset Management
Luxembourg
$4.59M
Fisher Asset Management
78
Fisher Asset Management
Washington
$4.57M
NAMI
79
Nomura Asset Management International
Pennsylvania
$4.21M
PP
80
PDT Partners
New York
$4.07M
Schroder Investment Management Group
81
Schroder Investment Management Group
United Kingdom
$4M
WP
82
Woodline Partners
California
$3.95M
Swiss National Bank
83
Swiss National Bank
Switzerland
$3.93M
TI
84
Trexquant Investment
Connecticut
$3.8M
Royal Bank of Canada
85
Royal Bank of Canada
Ontario, Canada
$3.75M
CCM
86
Catalio Capital Management
New York
$3.74M
WCM Investment Management
87
WCM Investment Management
California
$3.72M
Rafferty Asset Management
88
Rafferty Asset Management
New York
$3.61M
SEI Investments
89
SEI Investments
Pennsylvania
$3.54M
Susquehanna International Group
90
Susquehanna International Group
Pennsylvania
$3.5M
Capital Fund Management (CFM)
91
Capital Fund Management (CFM)
France
$3.45M
KAM
92
Krensavage Asset Management
New York
$3.44M
SOCM
93
SR One Capital Management
Pennsylvania
$3.17M
ECM
94
ExodusPoint Capital Management
New York
$3.16M
BGI
95
B Group Inc
Texas
$3.1M
DekaBank Deutsche Girozentrale
96
DekaBank Deutsche Girozentrale
Germany
$2.9M
CIAM
97
Caitong International Asset Management
Hong Kong
$2.83M
EMFAT
98
Emerald Mutual Fund Advisers Trust
Pennsylvania
$2.77M
XT
99
XTX Topco
Cayman Islands
$2.76M
Comerica Bank
100
Comerica Bank
Texas
$2.72M