|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$224M
|
+$1.61M
|
+57,074
|
+0.8%
|
|
|
2
|
TRV GP V
Boston,
Massachusetts
|
$223M
|
–
|
–
|
–
|
|
|
3
|
Arch Venture Management
Chicago,
Illinois
|
$117M
|
–
|
–
|
–
|
|
|
4
|
Capital International Investors
Los Angeles,
California
|
$96.9M
|
-$8.57M
|
-304,556
|
-9%
|
|
|
5
|
Cormorant Asset Management
Boston,
Massachusetts
|
$92.5M
|
-$1.97M
|
-70,000
|
-2%
|
|
|
6
|
|
$92.1M
|
-$1.68M
|
-59,628
|
-2%
|
|
|
7
|
|
$78.4M
|
+$2.08M
|
+74,093
|
+3%
|
|
|
8
|
Sofinnova Investments
Menlo Park,
California
|
$59.6M
|
–
|
–
|
–
|
|
|
9
|
Johnson & Johnson
New Brunswick,
New Jersey
|
$55.8M
|
–
|
–
|
–
|
|
|
10
|
Polar Capital Holdings
London,
United Kingdom
|
$51.4M
|
+$17.9M
|
+637,733
|
+63%
|
|
|
11
|
Baker Bros. Advisors
New York
|
$48.4M
|
–
|
–
|
–
|
|
|
12
|
Vestal Point Capital
New York
|
$44.9M
|
+$9.18M
|
+326,229
|
+29%
|
|
|
13
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$41.5M
|
+$37.3M
|
+1,325,082
|
New
|
|
|
14
|
TRV GP VI
Boston,
Massachusetts
|
$30.3M
|
–
|
–
|
–
|
|
|
15
|
|
$28.8M
|
-$942K
|
-33,505
|
-4%
|
|
|
16
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$27.1M
|
-$426K
|
-15,153
|
-2%
|
|
|
17
|
State Street
Boston,
Massachusetts
|
$23.8M
|
+$1.26M
|
+44,731
|
+6%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$22.6M
|
+$756K
|
+26,888
|
+4%
|
|
|
19
|
AllianceBernstein
Nashville,
Tennessee
|
$22.1M
|
-$1.7M
|
-60,568
|
-8%
|
|
|
20
|
Perceptive Advisors
New York
|
$21.1M
|
–
|
–
|
–
|
|
|
21
|
Siren LLC
Greenwich,
Connecticut
|
$20.1M
|
-$1.88M
|
-67,000
|
-9%
|
|
|
22
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$19.4M
|
+$44.2K
|
+1,571
|
+0.3%
|
|
|
23
|
Capital World Investors
Los Angeles,
California
|
$16.8M
|
+$15.1M
|
+536,607
|
New
|
|
|
24
|
Sio Capital Management
New York
|
$11.5M
|
+$5.11M
|
+181,544
|
+98%
|
|
|
25
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$10M
|
+$9.03M
|
+320,909
|
New
|
|
