|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$299M
|
+$145K
|
+3,955
|
+0.1%
|
|
|
2
|
TRV GP V
Boston,
Massachusetts
|
$262M
|
-$31.4M
|
-854,708
|
-12%
|
|
|
3
|
Arch Venture Management
Chicago,
Illinois
|
$155M
|
–
|
–
|
–
|
|
|
4
|
Capital International Investors
Los Angeles,
California
|
$122M
|
-$6.47M
|
-176,015
|
-6%
|
|
|
5
|
|
$121M
|
-$1.17M
|
-31,802
|
-1%
|
|
|
6
|
|
$113M
|
+$7.12M
|
+193,831
|
+8%
|
|
|
7
|
Cormorant Asset Management
Boston,
Massachusetts
|
$111M
|
-$11M
|
-300,000
|
-10%
|
|
|
8
|
Sofinnova Investments
Menlo Park,
California
|
$79.4M
|
–
|
–
|
–
|
|
|
9
|
Johnson & Johnson
New Brunswick,
New Jersey
|
$74.4M
|
–
|
–
|
–
|
|
|
10
|
Polar Capital Holdings
London,
United Kingdom
|
$67M
|
-$1.25M
|
-33,947
|
-2%
|
|
|
11
|
Baker Bros. Advisors
New York
|
$64.5M
|
–
|
–
|
–
|
|
|
12
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$56.1M
|
+$788K
|
+21,430
|
+2%
|
|
|
13
|
TRV GP VI
Boston,
Massachusetts
|
$40.4M
|
–
|
–
|
–
|
|
|
14
|
State Street
Boston,
Massachusetts
|
$34.1M
|
+$2.17M
|
+59,160
|
+8%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$33.1M
|
+$2.64M
|
+71,831
|
+10%
|
|
|
16
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$32.8M
|
-$2.9M
|
-79,010
|
-9%
|
|
|
17
|
Perceptive Advisors
New York
|
$32.2M
|
+$3.65M
|
+99,419
|
+15%
|
|
|
18
|
Vestal Point Capital
New York
|
$30.4M
|
-$26M
|
-706,229
|
-49%
|
|
|
19
|
|
$26.8M
|
-$10.1M
|
-274,784
|
-30%
|
|
|
20
|
Siren LLC
Greenwich,
Connecticut
|
$26.7M
|
–
|
–
|
–
|
|
|
21
|
Capital World Investors
Los Angeles,
California
|
$23M
|
+$553K
|
+15,050
|
+3%
|
|
|
22
|
AllianceBernstein
Nashville,
Tennessee
|
$21.7M
|
-$1.27M
|
-34,459
|
-5%
|
|
|
23
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$16.4M
|
-$8.36M
|
-227,400
|
-37%
|
|
|
24
|
Dimensional Fund Advisors
Austin,
Texas
|
$15.1M
|
+$5.06M
|
+137,616
|
+61%
|
|
|
25
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$15M
|
+$1.43M
|
+39,035
|
+12%
|
|
