|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$116M
|
+$115M
|
+4,983,351
|
New
|
|
|
2
|
Arch Venture Management
Chicago,
Illinois
|
$86.7M
|
+$86.3M
|
+3,728,738
|
New
|
|
|
3
|
Cormorant Asset Management
Boston,
Massachusetts
|
$68.4M
|
+$68.1M
|
+2,940,283
|
New
|
|
|
4
|
Capital International Investors
Los Angeles,
California
|
$60.5M
|
+$60.3M
|
+2,602,531
|
New
|
|
|
5
|
Johnson & Johnson
New Brunswick,
New Jersey
|
$58.1M
|
+$57.8M
|
+2,498,051
|
New
|
|
|
6
|
Sofinnova Investments
Menlo Park,
California
|
$45.4M
|
+$45.2M
|
+1,951,562
|
New
|
|
|
7
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$35.7M
|
+$35.5M
|
+1,535,151
|
New
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$31.6M
|
+$31.5M
|
+1,360,605
|
New
|
|
|
9
|
AllianceBernstein
Nashville,
Tennessee
|
$25.4M
|
+$25.3M
|
+1,090,858
|
New
|
|
|
10
|
Perceptive Advisors
New York
|
$17.4M
|
+$17.3M
|
+748,183
|
New
|
|
|
11
|
Citadel Advisors
Miami,
Florida
|
$13.2M
|
+$13.7M
|
+592,458
|
New
|
|
|
12
|
|
$8.14M
|
+$8.1M
|
+350,000
|
New
|
|
|
13
|
Logos Global Management
San Francisco,
California
|
$4.37M
|
+$4.84M
|
+208,910
|
New
|
|
|
14
|
Woodline Partners
San Francisco,
California
|
$3.98M
|
+$3.96M
|
+171,100
|
New
|
|
|
15
|
Millennium Management
New York
|
$2.72M
|
+$2.7M
|
+116,782
|
New
|
|
|
16
|
TD Asset Management
Toronto,
Ontario, Canada
|
$2.36M
|
+$2.35M
|
+101,522
|
New
|
|
|
17
|
Manulife (Manufacturers Life Insurance)
Canada,
Ontario, Canada
|
$1.76M
|
+$1.75M
|
+75,516
|
New
|
|
|
18
|
|
$1.63M
|
+$1.62M
|
+70,000
|
New
|
|
|
19
|
Saturn V Capital Management
Austin,
Texas
|
$1.63M
|
+$1.62M
|
+70,000
|
New
|
|
|
20
|
Vanguard Group
Malvern,
Pennsylvania
|
$1.63M
|
+$1.62M
|
+70,000
|
New
|
|
|
21
|
Eventide Asset Management
Boston,
Massachusetts
|
$1.16M
|
+$1.16M
|
+50,000
|
New
|
|
|
22
|
LMR Partners
London,
United Kingdom
|
$1.16M
|
+$1.16M
|
+50,000
|
New
|
|
|
23
|
Monashee Investment Management
Boston,
Massachusetts
|
$930K
|
+$926K
|
+40,000
|
New
|
|
|
24
|
Alyeska Investment Group
Chicago,
Illinois
|
$808K
|
+$804K
|
+34,731
|
New
|
|
|
25
|
Soros Fund Management
New York
|
$698K
|
+$695K
|
+30,000
|
New
|
|
