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Pyxis Oncology
PYXS

Overview Fund Activity

73 hedge funds and large institutions have $30.1M invested in Pyxis Oncology in 2025 Q2 according to their latest regulatory filings, with 15 funds opening new positions, 19 increasing their positions, 23 reducing their positions, and 29 closing their positions.

Holders
73
Holders Change
-15
Holders Change %
-17.05%
% of All Funds
0.98%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
15
Increased
19
Reduced
23
Closed
29
Calls
$16K
Puts
$2K
Net Calls
+$14K
Net Calls Change
+$9K

Top Buyers

1
TCM
1
Tang Capital Management
California
$2.75M
2
Millennium Management
2
Millennium Management
New York
$3.89M
3
Jane Street
3
Jane Street
New York
$370K
4
SC
4
Schulhoff & Co
Ohio
$303K
5
Marshall Wace
5
Marshall Wace
United Kingdom
$163K

Top Sellers

1
BlackRock
1
BlackRock
New York
$1.02M
2
State Street
2
State Street
Massachusetts
$205K
3
Geode Capital Management
3
Geode Capital Management
Massachusetts
$562K
4
IC
4
Ikarian Capital
Texas
$0
5
Vanguard Group
5
Vanguard Group
Pennsylvania
$2.36M
Name Market Value Shares Shares
Change 		Shares
Change %
P
1
Pfizer
New York
$7.74M 7,032,770 – –
LCM
2
Laurion Capital Management
New York
$3.99M 3,625,974 – –
Millennium Management
3
Millennium Management
New York
$3.89M 3,539,860 +1,054,584 +42%
TCM
4
Tang Capital Management
California
$2.75M 2,500,000 +1,400,000 +127%
Vanguard Group
5
Vanguard Group
Pennsylvania
$2.36M 2,149,396 -287,332 -12%
PAI
6
Palo Alto Investors
California
$1.14M 1,037,421 – –
BlackRock
7
BlackRock
New York
$1.02M 926,805 -2,345,169 -72%
Aberdeen Group
8
Aberdeen Group
United Kingdom
$1M 913,045 – –
6CM
9
683 Capital Management
New York
$600K 545,000 -5,000 -0.9%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$562K 510,963 -598,135 -54%
Renaissance Technologies
11
Renaissance Technologies
New York
$460K 417,822 -164,314 -28%
UBS Group
12
UBS Group
Switzerland
$436K 396,096 -748 -0.2%
P8IP
13
Pier 88 Investment Partners
California
$404K 367,170 -23,790 -6%
Jane Street
14
Jane Street
New York
$370K 336,084 +336,084 New
DC
15
Decheng Capital
California
$359K 326,810 – –
SC
16
Schulhoff & Co
Ohio
$303K 275,000 +153,000 +125%
Goldman Sachs
17
Goldman Sachs
New York
$247K 224,274 +63,444 +39%
State Street
18
State Street
Massachusetts
$205K 186,055 -746,143 -80%
Bank of New York Mellon
19
Bank of New York Mellon
New York
$182K 165,044 -107,725 -39%
Morgan Stanley
20
Morgan Stanley
New York
$176K 160,174 -286,308 -64%
Marshall Wace
21
Marshall Wace
United Kingdom
$163K 147,771 +147,771 New
BCM
22
Bridgeway Capital Management
Texas
$157K 142,295 +61,500 +76%
YIH
23
Y-Intercept (HK)
Hong Kong
$146K 133,047 +133,047 New
NW
24
NewEdge Wealth
Pennsylvania
$124K 116,006 – –
Qube Research & Technologies (QRT)
25
Qube Research & Technologies (QRT)
United Kingdom
$113K 103,063 +57,935 +128%
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