Jane Street’s Pyxis Oncology PYXS Stock Holding History

Jane Street’s Portfolio PYXS Stock Details PYXS Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$873K	Sell	290,090 -14,369	-5%	-$27.5K	﹤0.01%	6811
2026 Q1	$445K	Sell	304,459 -481,551	-61%	-$726K	﹤0.01%	8341
2025 Q4	$904K	Buy	786,010 +482,310	+159%	+$1.7M	﹤0.01%	6330
2025 Q3	$674K	Sell	303,700 -32,384	-10%	-$46.6K	﹤0.01%	7191
2025 Q2	$370K	Buy	+336,084	New	+$379K	﹤0.01%	7478
2025 Q1	–	Sell	-67,686	Closed	-$106K	–	10385
2024 Q4	$106K	Buy	67,686 +18,128	+37%	+$52.3K	﹤0.01%	8742
2024 Q3	$182K	Buy	49,558 +14,349	+41%	+$50.2K	﹤0.01%	8710
2024 Q2	$117K	Sell	35,209 -140,043	-80%	-$589K	﹤0.01%	8671
2024 Q1	$747K	Buy	175,252 +160,236	+1,067%	+$674K	﹤0.01%	5956
2023 Q4	$27K	Buy	+15,016	New	+$25.7K	﹤0.01%	8871
2023 Q2	–	Sell	-75,430	Closed	-$302K	–	9406
2023 Q1	$302K	Buy	+75,430	New	+$151K	﹤0.01%	7185

Other funds holding PYXS

GGI

GordonMD Global Investments Beverely Hills, California $207M AUM

Pfizer New York $170M AUM 191.09% 1-Year Est. Return

LCM

Laurion Capital Management New York $3.9B AUM 75.03% 1-Year Est. Return

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

HealthInvest Partners Stockholm, Sweden $372M AUM 59.89% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

PAI

Palo Alto Investors Palo Alto, California $724M AUM 96.91% 1-Year Est. Return

Marshall Wace London, United Kingdom $127B AUM 46.06% 1-Year Est. Return

Renaissance Technologies New York $72.6B AUM 54.88% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return

Jane Street's PYXS Position: Q2 2026 in Review

Jane Street reduced its Pyxis Oncology (PYXS) stake by 4.7% in Q2 2026, selling an estimated $27.5K and leaving 290,090 shares worth $873K. The position accounts for ﹤0.01% of the portfolio, ranked #6811.

Jane Street first reported a position in PYXS in Q1 2023 and has held it in 11 quarters since. The position peaked at $904K in Q4 2025. 76 funds tracked by Wall St. Rank hold PYXS as of Q2 2026.

Jane Street held 290,090 shares of Pyxis Oncology worth $873K as of Q2 2026.
Jane Street sold 14,369 Pyxis Oncology shares in Q2 2026, an estimated $27.5K.
Pyxis Oncology made up ﹤0.01% of Jane Street's portfolio in Q2 2026, its #6811 holding.
Jane Street first reported a position in Pyxis Oncology in Q1 2023 and has held it in 11 quarters since.
Jane Street's Pyxis Oncology position peaked at $904K in Q4 2025.
76 funds tracked by Wall St. Rank held Pyxis Oncology as of Q2 2026.

Based on Jane Street's 13F filing for Q2 2026, filed 14 Aug 2026.