PYXS icon

Pyxis Oncology

2.28 USD
+0.07
3.17%
At close Updated Sep 18, 11:46 AM EDT
1 day
3.17%
5 days
23.91%
1 month
83.87%
3 months
100%
6 months
115.09%
Year to date
34.91%
1 year
-37.7%
5 years
-82.73%
10 years
-82.73%
 

About: Pyxis Oncology Inc is a preclinical oncology company focused on developing an arsenal of next-generation therapeutics to target difficult-to-treat cancers and improve quality of life for patients. It develops the product candidates with the objective to directly kill tumor cells, and to address the underlying pathologies created by cancer that enable its uncontrollable proliferation and immune evasion.

Employees: 44

0
Funds holding %
of 7,463 funds
Analysts bullish %

Fund manager confidence

Based on 2025 Q2 regulatory disclosures by fund managers ($100M+ AUM)

700% more call options, than puts

Call options by funds: $16K | Put options by funds: $2K

2% more capital invested

Capital invested by funds: $29.6M [Q1] → $30.2M (+$571K) [Q2]

4.78% less ownership

Funds ownership: 49.11% [Q1] → 44.33% (-4.78%) [Q2]

13% less repeat investments, than reductions

Existing positions increased: 20 | Existing positions reduced: 23

16% less funds holding

Funds holding: 88 [Q1] → 74 (-14) [Q2]

48% less first-time investments, than exits

New positions opened: 15 | Existing positions closed: 29

50% less funds holding in top 10

Funds holding in top 10: 2 [Q1] → 1 (-1) [Q2]

Research analyst outlook

2 Wall Street Analysts provided 1 year price targets over the past 3 months

Low target
$5
119% upside
Avg. target
$5
119% upside
High target
$5
119% upside

2 analyst ratings

positive
100%
neutral
0%
negative
0%
Guggenheim
Brad Canino
$5
Buy
Initiated
4 Sep 2025
HC Wainwright & Co.
Swayampakula Ramakanth
$5
Buy
Reiterated
19 Aug 2025

Financial journalist opinion

Based on 3 articles about PYXS published over the past 30 days

Positive
Zacks Investment Research
3 days ago
Should You Buy Pyxis Oncology, Inc. (PYXS) After Golden Cross?
Pyxis Oncology, Inc. (PYXS) is looking like an interesting pick from a technical perspective, as the company reached a key level of support. Recently, PYXS's 50-day simple moving average crossed above its 200-day simple moving average, known as a "golden cross.
Should You Buy Pyxis Oncology, Inc. (PYXS) After Golden Cross?
Positive
Zacks Investment Research
10 days ago
Investing in Oncology: 3 Cancer Stocks With Promising Pipelines
Relay Therapeutics, Pyxis Oncology and Allogene Therapeutics drive cancer innovation with pivotal trials and promising drug candidates.
Investing in Oncology: 3 Cancer Stocks With Promising Pipelines
Neutral
GlobeNewsWire
28 days ago
Pyxis Oncology to Participate in September Investor and Industry Conferences
BOSTON, Aug. 21, 2025 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing antibody-drug conjugate (ADC) therapeutics for difficult-to-treat cancers, today announced that Lara S. Sullivan, M.D., President, Chief Executive Officer and Chief Medical Officer, will participate in the following upcoming conferences.
Pyxis Oncology to Participate in September Investor and Industry Conferences
Neutral
GlobeNewsWire
1 month ago
Pyxis Oncology Reports Second Quarter 2025 Financial Results and Provides Business Update
–  Phase 1 monotherapy expansion study of micvotabart pelidotin (MICVO) for recurrent and metastatic head and neck squamous cell carcinoma (R/M HNSCC) patients progressing well with preliminary data in second half of 2025 and first half of 2026
Pyxis Oncology Reports Second Quarter 2025 Financial Results and Provides Business Update
Neutral
GlobeNewsWire
2 months ago
Pyxis Oncology Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
BOSTON, June 30, 2025 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing next-generation antibody-drug conjugate (‘ADC') therapeutics for difficult-to-treat cancers, reported today that Pyxis Oncology's Compensation Committee of the Board of Directors granted stock options to purchase an aggregate of 246,238 shares of Pyxis Oncology's common stock to four newly hired employees. The awards were granted under the Pyxis Oncology, Inc. 2022 Inducement Plan (the ‘Plan') with a grant date of June 30, 2025, as an inducement material to the new employee entering employment with Pyxis Oncology, in accordance with Nasdaq Listing Rule 5635(c)(4).
Pyxis Oncology Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Neutral
GlobeNewsWire
4 months ago
Pyxis Oncology Reports First Quarter 2025 Financial Results and Provides Business Update
-  Announced robust preclinical data supporting the unique three-pronged mechanism of action of micvotabart pelidotin (MICVO, formerly PYX-201), driving anti-tumor activity via direct tumor killing, bystander effect and immunogenic cell death
Pyxis Oncology Reports First Quarter 2025 Financial Results and Provides Business Update
Neutral
GlobeNewsWire
4 months ago
Pyxis Oncology to Participate in Two Upcoming Investor Conferences
BOSTON, May 14, 2025 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing next-generation ADC therapeutics for difficult-to-treat cancers, today announced that Lara S. Sullivan, M.D., President, Chief Executive Officer and Chief Medical Officer, will participate in fireside chats and be available for one-on-one meetings with investors at the following two upcoming investor conferences.
Pyxis Oncology to Participate in Two Upcoming Investor Conferences
Neutral
GlobeNewsWire
4 months ago
Pyxis Oncology Presents Promising Preclinical Results Providing Proof of Mechanism of Micvotabart Pelidotin, the First-in-Concept Extracellular-Targeting ADC
Gene signatures associated with increased efficacy of micvotabart pelidotin (MICVO) due to greater linker cleavage were identified based on differential gene expression analysis of PDX responders/non-responders
Pyxis Oncology Presents Promising Preclinical Results Providing Proof of Mechanism of Micvotabart Pelidotin, the First-in-Concept Extracellular-Targeting ADC
Positive
Zacks Investment Research
4 months ago
5 Small Drug Stocks to Buy as Tariff-Related Uncertainty Looms
Innovation is at its peak for the Zacks Medical-Drugs industry. AUPH, HRTX, ESPR, PYXS and PSTV may prove to be good additions to one's portfolio.
5 Small Drug Stocks to Buy as Tariff-Related Uncertainty Looms
Positive
Zacks Investment Research
5 months ago
Top Cancer Stocks to Buy to Boost Your Portfolio's Health
If the cancer space appeals to you, it's time to consider stocks like Pyxis Oncology, Verastem Oncology and Relay Therapeutics.
Top Cancer Stocks to Buy to Boost Your Portfolio's Health
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