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Personalis

109 hedge funds and large institutions have $422M invested in Personalis in 2025 Q3 according to their latest regulatory filings, with 20 funds opening new positions, 31 increasing their positions, 35 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

25% more funds holding in top 10

Funds holding in top 10: 45 (+1)

25% more first-time investments, than exits

New positions opened: 20 | Existing positions closed: 16

6% more capital invested

Capital invested by funds: $397M → $422M (+$25.3M)

4.52% more ownership

Funds ownership: 68.45%72.96% (+4.5%)

4% more funds holding

Funds holding: 105109 (+4)

11% less repeat investments, than reductions

Existing positions increased: 31 | Existing positions reduced: 35

48% less call options, than puts

Call options by funds: $488K | Put options by funds: $942K

Holders
109
Holders Change
+4
Holders Change %
+3.81%
% of All Funds
1.43%
Holding in Top 10
5
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+25%
% of All Funds
0.07%
New
20
Increased
31
Reduced
35
Closed
16
Calls
$488K
Puts
$942K
Net Calls
-$454K
Net Calls Change
-$408K
Name Holding Trade Value Shares
Change
Change in
Stake
MC
1
Merck & Co
New Jersey
$91.6M
LMC
2
Lightspeed Management Company
California
$53.2M
AIM
3
ARK Investment Management
Florida
$51.6M +$4.57M +802,268 +11%
BlackRock
4
BlackRock
New York
$36.8M +$2.51M +440,806 +8%
ACM
5
AIGH Capital Management
Maryland
$25.4M +$957K +168,143 +5%
Vanguard Group
6
Vanguard Group
Pennsylvania
$19.6M -$744K -130,651 -4%
T. Rowe Price Investment Management
7
T. Rowe Price Investment Management
Maryland
$18.8M +$9.22M +1,619,121 +128%
Aberdeen Group
8
Aberdeen Group
United Kingdom
$15.6M +$3.58M +628,450 +36%
KCM
9
Kennedy Capital Management
Missouri
$12.6M +$7.29M +1,281,695 +196%
BWLSA
10
Blue Water Life Science Advisors
California
$10.9M
Geode Capital Management
11
Geode Capital Management
Massachusetts
$8.7M -$182K -32,057 -2%
Millennium Management
12
Millennium Management
New York
$7.89M +$683K +120,027 +11%
Dimensional Fund Advisors
13
Dimensional Fund Advisors
Texas
$6.35M +$1.07M +188,791 +24%
State Street
14
State Street
Massachusetts
$6.04M +$1.36M +238,763 +35%
Sumitomo Mitsui Trust Group
15
Sumitomo Mitsui Trust Group
Japan
$3.85M -$281K -49,424 -8%
NAMA
16
Nikko Asset Management Americas
New York
$3.85M -$247K -43,321 -7%
Goldman Sachs
17
Goldman Sachs
New York
$3.74M +$2.07M +364,315 +174%
SOMRS
18
State of Michigan Retirement System
Michigan
$3.22M
Renaissance Technologies
19
Renaissance Technologies
New York
$2.95M -$627K -110,200 -20%
Northern Trust
20
Northern Trust
Illinois
$2.57M -$35.3K -6,205 -2%
Morgan Stanley
21
Morgan Stanley
New York
$2.23M -$1.62M -284,404 -45%
HCM
22
Howland Capital Management
Massachusetts
$2.16M +$258K +45,365 +16%
N
23
Nuveen
North Carolina
$2.01M -$1.86M -326,891 -51%
Ameriprise
24
Ameriprise
Minnesota
$1.95M -$176K -30,840 -9%
UBS Group
25
UBS Group
Switzerland
$1.93M +$1M +175,750 +147%

PSNL Hedge Fund Activity: Q3 2025 in Review

109 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Personalis (PSNL) for Q3 2025, worth a combined $422M — up 6.4% from $397M a quarter earlier.

Buyers outnumbered sellers: 20 funds opened new PSNL positions and 16 closed out — a net gain of 4 holders — while 31 added to existing stakes and 35 trimmed.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $9.22M. The largest seller was ExodusPoint Capital Management, exiting entirely with an estimated $2.87M sold.

  • 109 institutional investors held Personalis (PSNL) as of Q3 2025, up from 105 in Q2 2025.
  • Funds reported $422M of Personalis stock for Q3 2025, up 6.4% quarter-over-quarter.
  • 20 funds opened new Personalis positions in Q3 2025 and 16 closed out, a net change of +4 holders.
  • The largest Personalis buyer in Q3 2025 was T. Rowe Price Investment Management, an estimated $9.22M added.
  • The largest Personalis seller in Q3 2025 was ExodusPoint Capital Management, an estimated $2.87M sold.

Based on aggregated 13F filings for Q3 2025.