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Personalis

105 hedge funds and large institutions have $397M invested in Personalis in 2025 Q2 according to their latest regulatory filings, with 33 funds opening new positions, 35 increasing their positions, 24 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed

106% more capital invested

Capital invested by funds: $192M → $397M (+$204M)

46% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 24

6.33% more ownership

Funds ownership: 62.12%68.45% (+6.3%)

6% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 31

1% more funds holding

Funds holding: 104105 (+1)

0% more funds holding in top 10

Funds holding in top 10: 44 (0)

6% less call options, than puts

Call options by funds: $753K | Put options by funds: $799K

Holders
105
Holders Change
+1
Holders Change %
+0.96%
% of All Funds
1.38%
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
33
Increased
35
Reduced
24
Closed
31
Calls
$753K
Puts
$799K
Net Calls
-$46K
Net Calls Change
-$104K
Name Holding Trade Value Shares
Change
Change in
Stake
MC
1
Merck & Co
New Jersey
$92.1M
LMC
2
Lightspeed Management Company
California
$53.5M
AIM
3
ARK Investment Management
Florida
$46.6M -$373K -80,274 -1%
BlackRock
4
BlackRock
New York
$34.1M +$10.2M +2,205,471 +74%
ACM
5
AIGH Capital Management
Maryland
$24.4M -$1.14M -244,990 -6%
Vanguard Group
6
Vanguard Group
Pennsylvania
$20.6M +$8.57M +1,846,470 +143%
Aberdeen Group
7
Aberdeen Group
United Kingdom
$11.5M +$254K +54,713 +3%
BWLSA
8
Blue Water Life Science Advisors
California
$11M +$2.33M +500,900 +43%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$8.96M +$3.95M +851,422 +166%
T. Rowe Price Investment Management
10
T. Rowe Price Investment Management
Maryland
$8.29M +$5.87M +1,264,455 New
Millennium Management
11
Millennium Management
New York
$7.16M +$1.02M +219,215 +25%
Dimensional Fund Advisors
12
Dimensional Fund Advisors
Texas
$5.15M +$696K +149,835 +24%
State Street
13
State Street
Massachusetts
$4.51M +$2.29M +492,321 +252%
KCM
14
Kennedy Capital Management
Missouri
$4.29M +$228K +49,093 +8%
Sumitomo Mitsui Trust Group
15
Sumitomo Mitsui Trust Group
Japan
$4.2M -$165K -35,554 -5%
N
16
Nuveen
North Carolina
$4.17M +$2.95M +635,571 New
NAMA
17
Nikko Asset Management Americas
New York
$4.16M -$193K -41,657 -6%
Morgan Stanley
18
Morgan Stanley
New York
$4.11M +$309K +66,502 +12%
Renaissance Technologies
19
Renaissance Technologies
New York
$3.69M -$2.18M -470,711 -46%
SOMRS
20
State of Michigan Retirement System
Michigan
$3.24M
ECM
21
ExodusPoint Capital Management
New York
$2.87M +$1.87M +403,197 +1,180%
WSCM
22
Wellington Shields Capital Management
New York
$2.8M
Northern Trust
23
Northern Trust
Illinois
$2.62M +$1.41M +302,950 +312%
Ameriprise
24
Ameriprise
Minnesota
$2.16M +$1.41M +303,933 +1,172%
WSC
25
Wellington Shields & Co
New York
$1.92M

PSNL Hedge Fund Activity: Q2 2025 in Review

105 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Personalis (PSNL) for Q2 2025, worth a combined $397M — up 106% from $192M a quarter earlier.

Buyers outnumbered sellers: 33 funds opened new PSNL positions and 31 closed out — a net gain of 2 holders — while 35 added to existing stakes and 24 trimmed.

The largest buyer was BlackRock, adding an estimated $10.2M. The largest seller was Susquehanna International Group, cutting an estimated $4.11M.

  • 105 institutional investors held Personalis (PSNL) as of Q2 2025, up from 104 in Q1 2025.
  • Funds reported $397M of Personalis stock for Q2 2025, up 106% quarter-over-quarter.
  • 33 funds opened new Personalis positions in Q2 2025 and 31 closed out, a net change of +2 holders.
  • The largest Personalis buyer in Q2 2025 was BlackRock, an estimated $10.2M added.
  • The largest Personalis seller in Q2 2025 was Susquehanna International Group, an estimated $4.11M sold.

Based on aggregated 13F filings for Q2 2025.