Personalis
PSNL
105 hedge funds and large institutions have $397M invested in Personalis in 2025 Q2 according to their latest regulatory filings, with 33 funds opening new positions, 35 increasing their positions, 24 reducing their positions, and 31 closing their positions.
106% more capital invested
Capital invested by funds: $192M → $397M (+$204M)
46% more repeat investments, than reductions
Existing positions increased: 35 | Existing positions reduced: 24
6.33% more ownership
Funds ownership: 62.12% → 68.45% (+6.3%)
6% more first-time investments, than exits
New positions opened: 33 | Existing positions closed: 31
1% more funds holding
Funds holding: 104 → 105 (+1)
0% more funds holding in top 10
Funds holding in top 10: 4 → 4 (0)
6% less call options, than puts
Call options by funds: $753K | Put options by funds: $799K
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
BlackRock
New York
|
+$10.2M |
| 2 |
Vanguard Group
Malvern,
Pennsylvania
|
+$8.57M |
| 3 |
T. Rowe Price Investment Management
Baltimore,
Maryland
|
+$5.87M |
| 4 |
Geode Capital Management
Boston,
Massachusetts
|
+$3.95M |
| 5 |
N
Nuveen
Charlotte,
North Carolina
|
+$2.95M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
-$4.11M |
| 2 |
Marshall Wace
London,
United Kingdom
|
-$2.44M |
| 3 |
Renaissance Technologies
New York
|
-$2.18M |
| 4 |
Qube Research & Technologies (QRT)
London,
United Kingdom
|
-$1.78M |
| 5 |
Jacobs Levy Equity Management
Florham Park,
New Jersey
|
-$1.52M |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
BHCM
126
Brevan Howard Capital Management
St. Helier,
Jersey
| – | -$77K | -21,924 | Closed |
|
127
Two Sigma Advisers
New York
| – | -$73K | -20,800 | Closed |
|
|
SP
128
SIH Partners
Wilmington,
Delaware
| – | -$70.1K | -19,966 | Closed |
|
129
Franklin Resources
San Mateo,
California
| – | -$64.9K | -18,490 | Closed |
|
|
DC
130
Diametric Capital
Boston,
Massachusetts
| – | -$64.7K | -18,444 | Closed |
|
131
Prudential Financial
Newark,
New Jersey
| – | -$64.4K | -18,350 | Closed |
|
|
WC
132
Wexford Capital
West Palm Beach,
Florida
| – | -$57.3K | -16,316 | Closed |
|
|
PCIA
133
Prime Capital Investment Advisors
Overland Park,
Kansas
| – | -$40.3K | -11,468 | Closed |
|
|
ADL
134
Asset Dedication LLC
San Francisco,
California
| – | -$1.4K | -400 | Closed |
|
|
BCM
135
Berbice Capital Management
Melville,
New York
| – | -$9.65K | -200 | Closed |
|
|
OP
136
ORG Partners
Roanoke,
Indiana
| – | -$345 | -100 | Closed |
|
PSNL Hedge Fund Activity: Q2 2025 in Review
105 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Personalis (PSNL) for Q2 2025, worth a combined $397M — up 106% from $192M a quarter earlier.
Buyers outnumbered sellers: 33 funds opened new PSNL positions and 31 closed out — a net gain of 2 holders — while 35 added to existing stakes and 24 trimmed.
The largest buyer was BlackRock, adding an estimated $10.2M. The largest seller was Susquehanna International Group, cutting an estimated $4.11M.
- 105 institutional investors held Personalis (PSNL) as of Q2 2025, up from 104 in Q1 2025.
- Funds reported $397M of Personalis stock for Q2 2025, up 106% quarter-over-quarter.
- 33 funds opened new Personalis positions in Q2 2025 and 31 closed out, a net change of +2 holders.
- The largest Personalis buyer in Q2 2025 was BlackRock, an estimated $10.2M added.
- The largest Personalis seller in Q2 2025 was Susquehanna International Group, an estimated $4.11M sold.
Based on aggregated 13F filings for Q2 2025.