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Personalis

105 hedge funds and large institutions have $397M invested in Personalis in 2025 Q2 according to their latest regulatory filings, with 33 funds opening new positions, 35 increasing their positions, 24 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed

106% more capital invested

Capital invested by funds: $192M → $397M (+$204M)

46% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 24

6.33% more ownership

Funds ownership: 62.12%68.45% (+6.3%)

6% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 31

1% more funds holding

Funds holding: 104105 (+1)

0% more funds holding in top 10

Funds holding in top 10: 44 (0)

6% less call options, than puts

Call options by funds: $753K | Put options by funds: $799K

Holders
105
Holders Change
+1
Holders Change %
+0.96%
% of All Funds
1.38%
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
33
Increased
35
Reduced
24
Closed
31
Calls
$753K
Puts
$799K
Net Calls
-$46K
Net Calls Change
-$104K
Name Holding Trade Value Shares
Change
Change in
Stake
S
101
SignatureFD
Georgia
$1.04K +$733 +158 New
RA
102
Rise Advisors
New York
$932 +$659 +142 New
PS
103
Principal Securities
Iowa
$879 -$283 -61 -31%
SS
104
SBI Securities
Japan
$433 -$664 -143 -68%
AF
105
Allworth Financial
California
$427 +$302 +65 New
Marshall Wace
106
Marshall Wace
United Kingdom
-$2.44M -696,286 Closed
Jane Street
107
Jane Street
New York
-$867K -247,012 Closed
Squarepoint
108
Squarepoint
New York
-$711K -202,490 Closed
HF
109
HRT Financial
New York
-$621K -177,094 Closed
TI
110
Trexquant Investment
Connecticut
-$432K -122,959 Closed
SSA
111
Schonfeld Strategic Advisors
New York
-$402K -114,531 Closed
EC
112
EntryPoint Capital
New York
-$294K -83,628 Closed
XT
113
XTX Topco
Cayman Islands
-$290K -82,666 Closed
DTL
114
Dynamic Technology Lab
Singapore
-$269K -76,729 Closed
OAC
115
OMERS Administration Corp
Ontario, Canada
-$264K -75,200 Closed
GCM
116
Graham Capital Management
Connecticut
-$204K -58,083 Closed
CC
117
Centiva Capital
New York
-$177K -50,527 Closed
Verition Fund Management
118
Verition Fund Management
Connecticut
-$158K -44,939 Closed
JG
119
Jain Global
New York
-$154K -43,777 Closed
JFG
120
Jefferies Financial Group
New York
-$139K -39,600 Closed
BCM
121
Bridgeway Capital Management
Texas
-$107K -30,600 Closed
QC
122
Quantessence Capital
New York
-$100K -28,495 Closed
EGM
123
Engineers Gate Manager
New York
-$87.5K -24,920 Closed
LP
124
LMR Partners
United Kingdom
-$85.1K -24,232 Closed
MCM
125
Massar Capital Management
Connecticut
-$84.1K -23,973 Closed

PSNL Hedge Fund Activity: Q2 2025 in Review

105 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Personalis (PSNL) for Q2 2025, worth a combined $397M — up 106% from $192M a quarter earlier.

Buyers outnumbered sellers: 33 funds opened new PSNL positions and 31 closed out — a net gain of 2 holders — while 35 added to existing stakes and 24 trimmed.

The largest buyer was BlackRock, adding an estimated $10.2M. The largest seller was Susquehanna International Group, cutting an estimated $4.11M.

  • 105 institutional investors held Personalis (PSNL) as of Q2 2025, up from 104 in Q1 2025.
  • Funds reported $397M of Personalis stock for Q2 2025, up 106% quarter-over-quarter.
  • 33 funds opened new Personalis positions in Q2 2025 and 31 closed out, a net change of +2 holders.
  • The largest Personalis buyer in Q2 2025 was BlackRock, an estimated $10.2M added.
  • The largest Personalis seller in Q2 2025 was Susquehanna International Group, an estimated $4.11M sold.

Based on aggregated 13F filings for Q2 2025.