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Personalis

105 hedge funds and large institutions have $397M invested in Personalis in 2025 Q2 according to their latest regulatory filings, with 33 funds opening new positions, 35 increasing their positions, 24 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed

106% more capital invested

Capital invested by funds: $192M → $397M (+$204M)

46% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 24

6.33% more ownership

Funds ownership: 62.12%68.45% (+6.3%)

6% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 31

1% more funds holding

Funds holding: 104105 (+1)

0% more funds holding in top 10

Funds holding in top 10: 44 (0)

6% less call options, than puts

Call options by funds: $753K | Put options by funds: $799K

Holders
105
Holders Change
+1
Holders Change %
+0.96%
% of All Funds
1.38%
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
33
Increased
35
Reduced
24
Closed
31
Calls
$753K
Puts
$799K
Net Calls
-$46K
Net Calls Change
-$104K
Name Holding Trade Value Shares
Change
Change in
Stake
HSBC Holdings
51
HSBC Holdings
United Kingdom
$373K +$71.7K +15,447 +40%
Stifel Financial
52
Stifel Financial
Missouri
$328K +$46.4K +10,000 +25%
Man Group
53
Man Group
United Kingdom
$324K +$229K +49,373 New
M1FG
54
Mach-1 Financial Group
Arkansas
$320K +$227K +48,822 New
SPS
55
Susquehanna Portfolio Strategies
Pennsylvania
$315K +$123K +26,532 +124%
Jacobs Levy Equity Management
56
Jacobs Levy Equity Management
New Jersey
$260K -$1.52M -327,333 -89%
Acadian Asset Management
57
Acadian Asset Management
Massachusetts
$256K -$1.26M -271,364 -87%
Wells Fargo
58
Wells Fargo
California
$252K +$176K +37,937 +7,268%
Invesco
59
Invesco
Georgia
$243K +$108K +23,233 +168%
Deutsche Bank
60
Deutsche Bank
Germany
$216K +$153K +32,867 New
GAA
61
Green Alpha Advisors
Colorado
$209K -$25.3K -5,444 -15%
MIM
62
MetLife Investment Management
New Jersey
$200K +$141K +30,471 New
JP Morgan Chase
63
JP Morgan Chase
New York
$193K +$114K +24,621 +506%
AllianceBernstein
64
AllianceBernstein
Tennessee
$188K +$133K +28,700 New
IIM
65
INTECH Investment Management
Florida
$173K +$122K +26,317 New
AG
66
Algert Global
California
$165K +$117K +25,200 New
IC
67
IEQ Capital
California
$144K
Qube Research & Technologies (QRT)
68
Qube Research & Technologies (QRT)
United Kingdom
$126K -$1.78M -383,039 -95%
Manulife (Manufacturers Life Insurance)
69
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$123K +$87.1K +18,757 New
CUAMC
70
China Universal Asset Management Company
China
$116K +$167 +36 +0.2%
PA
71
Parallel Advisors
California
$108K
Mariner
72
Mariner
Kansas
$107K +$76.1K +16,386 New
New York State Common Retirement Fund
73
New York State Common Retirement Fund
New York
$104K +$73.3K +15,800 New
VOYA Investment Management
74
VOYA Investment Management
Georgia
$92.1K +$65.2K +14,036 New
ProShare Advisors
75
ProShare Advisors
Maryland
$89.1K +$63K +13,581 New

PSNL Hedge Fund Activity: Q2 2025 in Review

105 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Personalis (PSNL) for Q2 2025, worth a combined $397M — up 106% from $192M a quarter earlier.

Buyers outnumbered sellers: 33 funds opened new PSNL positions and 31 closed out — a net gain of 2 holders — while 35 added to existing stakes and 24 trimmed.

The largest buyer was BlackRock, adding an estimated $10.2M. The largest seller was Susquehanna International Group, cutting an estimated $4.11M.

  • 105 institutional investors held Personalis (PSNL) as of Q2 2025, up from 104 in Q1 2025.
  • Funds reported $397M of Personalis stock for Q2 2025, up 106% quarter-over-quarter.
  • 33 funds opened new Personalis positions in Q2 2025 and 31 closed out, a net change of +2 holders.
  • The largest Personalis buyer in Q2 2025 was BlackRock, an estimated $10.2M added.
  • The largest Personalis seller in Q2 2025 was Susquehanna International Group, an estimated $4.11M sold.

Based on aggregated 13F filings for Q2 2025.