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Personalis

104 hedge funds and large institutions have $192M invested in Personalis in 2025 Q1 according to their latest regulatory filings, with 19 funds opening new positions, 43 increasing their positions, 26 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

65% more repeat investments, than reductions

Existing positions increased: 43 | Existing positions reduced: 26

14% more call options, than puts

Call options by funds: $462K | Put options by funds: $404K

0% more funds holding in top 10

Funds holding in top 10: 44 (0)

10% less first-time investments, than exits

New positions opened: 19 | Existing positions closed: 21

3% less funds holding

Funds holding: 107104 (-3)

10.55% less ownership

Funds ownership: 72.67%62.12% (-11%)

35% less capital invested

Capital invested by funds: $298M → $192M (-$106M)

Holders
104
Holders Change
-3
Holders Change %
-2.8%
% of All Funds
1.39%
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
19
Increased
43
Reduced
26
Closed
21
Calls
$462K
Puts
$404K
Net Calls
+$58K
Net Calls Change
+$87K
Name Holding Trade Value Shares
Change
Change in
Stake
HCM
26
Howland Capital Management
Massachusetts
$993K +$96K +20,200 +8%
PCM
27
Perkins Capital Management
Minnesota
$903K
BC
28
Bruce & Co
Illinois
$888K
Jane Street
29
Jane Street
New York
$867K -$733K -154,302 -38%
Squarepoint
30
Squarepoint
New York
$711K +$527K +110,806 +121%
Bank of America
31
Bank of America
North Carolina
$706K -$54.8K -11,525 -5%
State Street
32
State Street
Massachusetts
$685K -$14.7K -3,100 -2%
HF
33
HRT Financial
New York
$621K +$842K +177,094 New
SFI
34
Susquehanna Fundamental Investments
Pennsylvania
$541K +$554K +116,481 +309%
LPL Financial
35
LPL Financial
California
$519K +$19K +4,000 +3%
GCP
36
GSA Capital Partners
United Kingdom
$508K +$277K +58,333 +68%
WJWM
37
Williams Jones Wealth Management
New York
$471K
TI
38
Trexquant Investment
Connecticut
$432K +$479K +100,804 +455%
SSA
39
Schonfeld Strategic Advisors
New York
$402K +$476K +100,171 +698%
Two Sigma Investments
40
Two Sigma Investments
New York
$387K -$168K -35,456 -24%
Northern Trust
41
Northern Trust
Illinois
$341K +$38.2K +8,034 +9%
Barclays
42
Barclays
United Kingdom
$302K -$111K -23,377 -21%
T. Rowe Price Associates
43
T. Rowe Price Associates
Maryland
$299K -$47.5K -10,000 -11%
EC
44
EntryPoint Capital
New York
$294K +$172K +36,115 +76%
XT
45
XTX Topco
Cayman Islands
$290K +$234K +49,197 +147%
Royal Bank of Canada
46
Royal Bank of Canada
Ontario, Canada
$275K +$11.4K +2,395 +3%
DTL
47
Dynamic Technology Lab
Singapore
$269K +$157K +33,044 +76%
OAC
48
OMERS Administration Corp
Ontario, Canada
$264K -$29.5K -6,200 -8%
American Century Companies
49
American Century Companies
Missouri
$236K +$81.1K +17,056 +34%
GCM
50
Graham Capital Management
Connecticut
$204K +$276K +58,083 New

PSNL Hedge Fund Activity: Q1 2025 in Review

104 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Personalis (PSNL) for Q1 2025, worth a combined $192M — down 35% from $298M a quarter earlier.

Sellers outnumbered buyers: 21 funds closed out of PSNL and 19 opened new positions — a net loss of 2 holders — while 26 trimmed existing stakes and 43 added.

The largest buyer was Aberdeen Group, adding an estimated $6.69M. The largest seller was Millennium Management, cutting an estimated $2.12M.

  • 104 institutional investors held Personalis (PSNL) as of Q1 2025, down from 107 in Q4 2024.
  • Funds reported $192M of Personalis stock for Q1 2025, down 35% quarter-over-quarter.
  • 19 funds opened new Personalis positions in Q1 2025 and 21 closed out, a net change of -2 holders.
  • The largest Personalis buyer in Q1 2025 was Aberdeen Group, an estimated $6.69M added.
  • The largest Personalis seller in Q1 2025 was Millennium Management, an estimated $2.12M sold.

Based on aggregated 13F filings for Q1 2025.