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Prime Medicine
PRME

Name Holding Trade Value Shares
Change 		Change in
Stake
GCM
26
Ghisallo Capital Management
Massachusetts
$1.3M +$1.26M +70,000 New
LCM
27
Laurion Capital Management
New York
$1.11M +$1.08M +60,000 New
Manulife (Manufacturers Life Insurance)
28
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$887K +$813K +44,989 New
Bank of America
29
Bank of America
North Carolina
$880K +$855K +47,359 New
PMEF
30
Point72 Middle East FZE
United Arab Emirates
$699K +$679K +37,609 New
BM
31
Brandywine Managers
Delaware
$613K +$596K +32,977 New
Walleye Capital
32
Walleye Capital
New York
$557K +$542K +30,000 New
Bank of New York Mellon
33
Bank of New York Mellon
New York
$539K +$524K +29,016 New
TD Asset Management
34
TD Asset Management
Ontario, Canada
$444K +$432K +23,922 New
Morgan Stanley
35
Morgan Stanley
New York
$379K +$368K +20,389 New
LP
36
LMR Partners
United Kingdom
$330K +$321K +17,760 New
CGL
37
Clarius Group LLC
Washington
$299K +$290K +16,080 New
Nuveen
38
Nuveen
North Carolina
$262K +$255K +14,128 New
OC
39
Oppenheimer & Co
New York
$260K +$253K +14,012 New
LCS
40
Levin Capital Strategies
New York
$197K +$191K +10,585 New
SIM
41
Sandia Investment Management
Massachusetts
$186K +$181K +10,000 New
JP Morgan Chase
42
JP Morgan Chase
New York
$184K +$178K +9,874 New
PCM
43
Penserra Capital Management
California
$140K +$137K +7,570 New
MIM
44
MetLife Investment Management
New Jersey
$113K +$110K +6,091 New
Osaic Holdings
45
Osaic Holdings
Arizona
$112K +$109K +6,029 New
New York State Common Retirement Fund
46
New York State Common Retirement Fund
New York
$92.9K +$90.3K +5,000 New
AIG
47
American International Group
New York
$91.2K +$88.7K +4,909 New
Deutsche Bank
48
Deutsche Bank
Germany
$83.1K +$80.8K +4,473 New
California State Teachers Retirement System (CalSTRS)
49
California State Teachers Retirement System (CalSTRS)
California
$77K +$74.9K +4,144 New
APP
50
Alpha Paradigm Partners
Illinois
$72K +$70.4K +3,895 New
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