We are live on ! Find out more
PEPG icon

PepGen
PEPG

87 hedge funds and large institutions have $373M invested in PepGen in 2025 Q4 according to their latest regulatory filings, with 29 funds opening new positions, 27 increasing their positions, 17 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more call options, than puts

Call options by funds: $5.31M | Put options by funds: $1.77M

142% more first-time investments, than exits

New positions opened: 29 | Existing positions closed: 12

59% more repeat investments, than reductions

Existing positions increased: 27 | Existing positions reduced: 17

43% more capital invested

Capital invested by funds: $262M → $373M (+$111M)

21% more funds holding

Funds holding: 72 → 87 (+15)

89.51% less ownership

Funds ownership: 172.95% → 83.44% (-90%)

Holders
87
Holders Change
+15
Holders Change %
+20.83%
% of All Funds
1.06%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
29
Increased
27
Reduced
17
Closed
12
Calls
$5.31M
Puts
$1.77M
Net Calls
+$3.54M
Net Calls Change
-$1.51M

Top Buyers

Rank Fund Capital Flow
1
NCM
Nantahala Capital Management
Connecticut
+$8.03M
2
CC
Commodore Capital
New York
+$5.41M
3
Pictet Asset Management
Pictet Asset Management
Switzerland
+$4.52M
4
BlackRock
BlackRock
New York
+$4.07M
5
Morgan Stanley
Morgan Stanley
New York
+$2.64M

Top Sellers

Rank Fund Capital Flow
1
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$7.01M
2
RI
RTW Investments
New York
-$6.93M
3
DTC
Deep Track Capital
Connecticut
-$5.54M
4
TCM
TCG Crossover Management
California
-$5.54M
5
EC
EcoR1 Capital
California
-$3.7M
Name Holding Trade Value Shares
Change 		Change in
Stake
Marshall Wace
26
Marshall Wace
United Kingdom
$1.89M +$1.51M +290,589 New
Citadel Advisors
27
Citadel Advisors
Florida
$1.74M -$153K -29,469 -10%
Two Sigma Investments
28
Two Sigma Investments
New York
$1.74M +$908K +174,932 +189%
Walleye Capital
29
Walleye Capital
New York
$1.67M +$1.33M +255,974 New
Goldman Sachs
30
Goldman Sachs
New York
$1.57M +$1.25M +241,618 New
State Street
31
State Street
Massachusetts
$1.42M +$787K +151,700 +231%
AGP
32
Artia Global Partners
Florida
$1.34M +$1.07M +205,324 New
Millennium Management
33
Millennium Management
New York
$1.29M -$1.57M -302,323 -60%
Jane Street
34
Jane Street
New York
$1.25M +$1M +192,733 New
6CM
35
683 Capital Management
New York
$1.22M +$970K +186,916 New
PCMH
36
Polymer Capital Management (HK)
Hong Kong
$1.04M +$830K +160,000 New
Renaissance Technologies
37
Renaissance Technologies
New York
$963K +$375K +72,200 +95%
MCM
38
Monimus Capital Management
New Jersey
$901K +$174K +33,598 +32%
Dimensional Fund Advisors
39
Dimensional Fund Advisors
Texas
$880K +$530K +102,210 +310%
Susquehanna International Group
40
Susquehanna International Group
Pennsylvania
$817K -$31.8K -6,134 -5%
SFM
41
Sphera Funds Management
Israel
$791K -$259K -50,000 -29%
ECM
42
ExodusPoint Capital Management
New York
$786K -$361K -69,528 -37%
Northern Trust
43
Northern Trust
Illinois
$770K +$305K +58,731 +99%
RAM
44
Readystate Asset Management
Illinois
$739K +$589K +113,502 New
Adage Capital Partners
45
Adage Capital Partners
Massachusetts
$651K -$7.01M -1,350,000 -93%
XT
46
XTX Topco
Cayman Islands
$638K +$509K +98,036 New
RC
47
RBF Capital
California
$619K -$25.7K -4,958 -5%
BNP Paribas Financial Markets
48
BNP Paribas Financial Markets
France
$583K +$458K +88,179 +6,317%
Connor, Clark & Lunn Investment Management (CC&L)
49
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$477K +$183K +35,225 +93%
Hudson Bay Capital Management
50
Hudson Bay Capital Management
Connecticut
$452K +$360K +69,391 New
1
2
3 4

PEPG Hedge Fund Activity: Q4 2025 in Review

87 of the 8,226 institutional investors tracked by Wall St. Rank reported a position in PepGen (PEPG) for Q4 2025, worth a combined $373M — up 43% from $262M a quarter earlier.

Buyers outnumbered sellers: 29 funds opened new PEPG positions and 12 closed out — a net gain of 17 holders — while 27 added to existing stakes and 17 trimmed.

The largest buyer was Nantahala Capital Management, opening a new position worth an estimated $8.03M. The largest seller was Adage Capital Partners, cutting an estimated $7.01M.

  • 87 institutional investors held PepGen (PEPG) as of Q4 2025, up from 72 in Q3 2025.
  • Funds reported $373M of PepGen stock for Q4 2025, up 43% quarter-over-quarter.
  • 29 funds opened new PepGen positions in Q4 2025 and 12 closed out, a net change of +17 holders.
  • The largest PepGen buyer in Q4 2025 was Nantahala Capital Management, an estimated $8.03M added.
  • The largest PepGen seller in Q4 2025 was Adage Capital Partners, an estimated $7.01M sold.

Based on aggregated 13F filings for Q4 2025.