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Puma Biotechnology
PBYI

Overview Fund Activity

116 hedge funds and large institutions have $90M invested in Puma Biotechnology in 2025 Q1 according to their latest regulatory filings, with 25 funds opening new positions, 44 increasing their positions, 25 reducing their positions, and 19 closing their positions.

Holders
116
Holders Change
+5
Holders Change %
+4.5%
% of All Funds
1.58%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
25
Increased
44
Reduced
25
Closed
19
Calls
$178K
Puts
$10K
Net Calls
+$168K
Net Calls Change
+$47K

Top Buyers

1
Arrowstreet Capital
1
Arrowstreet Capital
Massachusetts
$1.06M
2
D.E. Shaw & Co
2
D.E. Shaw & Co
New York
$1.69M
3
Connor, Clark & Lunn Investment Management (CC&L)
3
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$2.46M
4
Prudential Financial
4
Prudential Financial
New Jersey
$912K
5
American Century Companies
5
American Century Companies
Missouri
$3.4M

Top Sellers

1
EP
1
Eversept Partners
New York
$816K
2
Millennium Management
2
Millennium Management
New York
$4.1M
3
Citadel Advisors
3
Citadel Advisors
Florida
$0
4
JPMorgan Chase & Co
4
JPMorgan Chase & Co
New York
$143K
5
Squarepoint
5
Squarepoint
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
ACA
1
Acorn Capital Advisors
New York
$11.7M 3,940,052 – –
BlackRock
2
BlackRock
New York
$11.4M 3,847,368 +23,563 +0.6%
Vanguard Group
3
Vanguard Group
Pennsylvania
$10.9M 3,669,263 +25,841 +0.7%
Acadian Asset Management
4
Acadian Asset Management
Massachusetts
$5.94M 2,008,146 +36,018 +2%
Renaissance Technologies
5
Renaissance Technologies
New York
$5.41M 1,829,213 +73,700 +4%
Millennium Management
6
Millennium Management
New York
$4.1M 1,385,194 -508,932 -27%
American Century Companies
7
American Century Companies
Missouri
$3.4M 1,149,660 +201,284 +21%
Geode Capital Management
8
Geode Capital Management
Massachusetts
$2.83M 955,456 +36,021 +4%
KCM
9
Kennedy Capital Management
Missouri
$2.7M 911,123 +101,748 +13%
Dimensional Fund Advisors
10
Dimensional Fund Advisors
Texas
$2.63M 888,663 +24,903 +3%
Connor, Clark & Lunn Investment Management (CC&L)
11
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$2.46M 831,689 +344,321 +71%
State Street
12
State Street
Massachusetts
$1.92M 649,792 +39,850 +7%
D.E. Shaw & Co
13
D.E. Shaw & Co
New York
$1.69M 571,665 +349,057 +157%
GC
14
Globeflex Capital
California
$1.34M 452,606 – –
Los Angeles Capital Management
15
Los Angeles Capital Management
California
$1.2M 406,854 +121,175 +42%
Arrowstreet Capital
16
Arrowstreet Capital
Massachusetts
$1.06M 358,621 +358,621 New
SEI Investments
17
SEI Investments
Pennsylvania
$1.03M 347,679 +36,018 +12%
Bank of New York Mellon
18
Bank of New York Mellon
New York
$1.01M 340,886 +9,033 +3%
Northern Trust
19
Northern Trust
Illinois
$940K 317,438 -7,979 -2%
Prudential Financial
20
Prudential Financial
New Jersey
$912K 308,155 +201,870 +190%
Goldman Sachs
21
Goldman Sachs
New York
$871K 294,243 -19,854 -6%
UBS Group
22
UBS Group
Switzerland
$828K 279,667 +124,096 +80%
EP
23
Eversept Partners
New York
$816K 275,788 -720,314 -72%
Morgan Stanley
24
Morgan Stanley
New York
$777K 262,538 -7,796 -3%
Two Sigma Advisers
25
Two Sigma Advisers
New York
$731K 246,800 +49,900 +25%
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