Squarepoint’s Puma Biotechnology PBYI Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2025
Q4
Sell
-21,334
Closed -$113K 4720
2025
Q3
$113K Buy
21,334
+3,540
+20% +$15K ﹤0.01% 4086
2025
Q2
$61K Buy
+17,794
New +$56.8K ﹤0.01% 4276
2025
Q1
Sell
-75,929
Closed -$232K 5201
2024
Q4
$232K Sell
75,929
-23,318
-23% -$67.8K ﹤0.01% 4358
2024
Q3
$253K Buy
99,247
+27,856
+39% +$84.3K ﹤0.01% 3559
2024
Q2
$233K Buy
71,391
+10,757
+18% +$47.2K ﹤0.01% 3571
2024
Q1
$321K Buy
60,634
+32,236
+114% +$174K ﹤0.01% 3333
2023
Q4
$123K Sell
28,398
-28,180
-50% -$93.4K ﹤0.01% 3717
2023
Q3
$149K Sell
56,578
-34,409
-38% -$117K ﹤0.01% 3491
2023
Q2
$321K Buy
90,987
+74,137
+440% +$231K ﹤0.01% 2925
2023
Q1
$52.1K Sell
16,850
-1,043
-6% -$3.93K ﹤0.01% 3050
2022
Q4
$75.7K Buy
+17,893
New +$61.7K ﹤0.01% 2996
2022
Q1
Sell
-38,201
Closed -$116K 3349
2021
Q4
$116K Sell
38,201
-61,156
-62% -$265K ﹤0.01% 2883
2021
Q3
$696K Buy
99,357
+22,431
+29% +$168K ﹤0.01% 1776
2021
Q2
$706K Buy
76,926
+37,226
+94% +$377K ﹤0.01% 1881
2021
Q1
$386K Sell
39,700
-14,428
-27% -$161K ﹤0.01% 2221
2020
Q4
$555K Buy
54,128
+34,425
+175% +$349K ﹤0.01% 1740
2020
Q3
$199K Buy
19,703
+3,045
+18% +$31K ﹤0.01% 2096
2020
Q2
$174K Buy
+16,658
New +$172K ﹤0.01% 1866
2020
Q1
Sell
-130,773
Closed -$1.14M 2348
2019
Q4
$1.14M Sell
130,773
-39,154
-23% -$324K 0.01% 1249
2019
Q3
$1.83M Sell
169,927
-18,225
-10% -$197K 0.02% 885
2019
Q2
$2.39M Buy
188,152
+158,862
+542% +$3.66M 0.02% 749
2019
Q1
$1.14M Sell
29,290
-1,475
-5% -$45K 0.01% 1038
2018
Q4
$626K Sell
30,765
-9,426
-23% -$283K 0.01% 1140
2018
Q3
$1.84M Buy
+40,191
New +$1.94M 0.02% 757
2018
Q1
Sell
-10,626
Closed -$1.05M 2022
2017
Q4
$1.05M Buy
10,626
+1,955
+23% +$219K 0.02% 809
2017
Q3
$1.04M Sell
8,671
-14,263
-62% -$1.33M 0.02% 712
2017
Q2
$2M Buy
22,934
+171
+0.8% +$9.57K 0.04% 516
2017
Q1
$847K Sell
22,763
-1,371
-6% -$50K 0.02% 668
2016
Q4
$741K Buy
24,134
+20,430
+552% +$883K 0.03% 623
2016
Q3
$248K Buy
+3,704
New +$187K 0.02% 814
2015
Q3
Sell
-9,627
Closed -$1.12M 536
2015
Q2
$1.12M Buy
+9,627
New +$1.74M 0.36% 71

Other funds holding PBYI

Squarepoint's PBYI Position: Q4 2025 in Review

Squarepoint sold out of Puma Biotechnology (PBYI) in Q4 2025, closing a stake of 21,334 shares — an estimated $113K sold.

Squarepoint first reported a position in PBYI in Q2 2015 and held it in 31 quarters. The position peaked at $2.39M in Q2 2019. 151 funds tracked by Wall St. Rank hold PBYI as of Q4 2025.

  • Squarepoint reported no remaining Puma Biotechnology position as of Q4 2025 after selling out during the quarter.
  • Squarepoint sold 21,334 Puma Biotechnology shares in Q4 2025, an estimated $113K.
  • Squarepoint first reported a position in Puma Biotechnology in Q2 2015 and held it in 31 quarters.
  • Squarepoint's Puma Biotechnology position peaked at $2.39M in Q2 2019.
  • 151 funds tracked by Wall St. Rank held Puma Biotechnology as of Q4 2025.

Based on Squarepoint's 13F filing for Q4 2025, filed 13 Feb 2026.