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Puma Biotechnology
PBYI

Overview Fund Activity

116 hedge funds and large institutions have $90M invested in Puma Biotechnology in 2025 Q1 according to their latest regulatory filings, with 25 funds opening new positions, 44 increasing their positions, 25 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
116
Holders Change
+5
Holders Change %
+4.5%
% of All Funds
1.58%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
25
Increased
44
Reduced
25
Closed
19
Calls
$178K
Puts
$10K
Net Calls
+$168K
Net Calls Change
+$47K

Top Buyers

1
Arrowstreet Capital
Arrowstreet Capital
Massachusetts
$1.06M
2
D.E. Shaw & Co
D.E. Shaw & Co
New York
$1.69M
3
Connor, Clark & Lunn Investment Management (CC&L)
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$2.46M
4
Prudential Financial
Prudential Financial
New Jersey
$912K
5
American Century Companies
American Century Companies
Missouri
$3.4M

Top Sellers

1
EP
Eversept Partners
New York
$816K
2
Millennium Management
Millennium Management
New York
$4.1M
3
Citadel Advisors
Citadel Advisors
Florida
$0
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
$143K
5
Squarepoint
Squarepoint
New York
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
HT
101
Headlands Technologies
Illinois
$3.6K +$3.6K +1,217 New
GIA
102
GHP Investment Advisors
Colorado
$3.46K – – –
GWSG
103
GPS Wealth Strategies Group
Colorado
$2.96K – – –
CIBC Private Wealth Group
104
CIBC Private Wealth Group
Georgia
$2.24K – – –
FDW
105
Fourth Dimension Wealth
Ohio
$2.07K – – –
SCM
106
Sterling Capital Management
North Carolina
$1.5K -$1.25K -421 -45%
Nisa Investment Advisors
107
Nisa Investment Advisors
Missouri
$1.23K -$234 -79 -16%
W
108
WealthCollab
Washington
$921 +$921 +311 New
CCM
109
Coldstream Capital Management
Washington
$900 +$900 +304 New
US Bancorp
110
US Bancorp
Minnesota
$592 – – –
TWD
111
True Wealth Design
Ohio
$421 +$350 +118 +492%
SC
112
SouthState Corp
Florida
$329 +$329 +111 New
SS
113
SBI Securities
Japan
$166 – – –
IA
114
IFP Advisors
Florida
$41 – – –
EWA
115
EverSource Wealth Advisors
Alabama
$18 +$18 +6 New
EWP
116
Elevation Wealth Partners
California
$9 – – –
Citadel Advisors
117
Citadel Advisors
Florida
– -$486K -159,425 Closed
Squarepoint
118
Squarepoint
New York
– -$232K -75,929 Closed
PAM
119
Panagora Asset Management
Massachusetts
– -$179K -58,849 Closed
WG
120
Winton Group
United Kingdom
– -$117K -38,241 Closed
SSA
121
Schonfeld Strategic Advisors
New York
– -$108K -35,300 Closed
CSS
122
Cubist Systematic Strategies
Connecticut
– -$99.5K -32,615 Closed
SG Americas Securities
123
SG Americas Securities
New York
– -$75K -24,668 Closed
Jane Street
124
Jane Street
New York
– -$68.6K -22,480 Closed
SOW
125
State of Wyoming
Wyoming
– -$62.3K -20,426 Closed
2 3 4
5
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