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Omeros
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Overview Fund Activity

136 hedge funds and large institutions have $227M invested in Omeros in 2025 Q1 according to their latest regulatory filings, with 22 funds opening new positions, 34 increasing their positions, 50 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
136
Holders Change
+8
Holders Change %
+6.25%
% of All Funds
1.85%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
22
Increased
34
Reduced
50
Closed
12
Calls
$4.15M
Puts
$6.34M
Net Calls
-$2.19M
Net Calls Change
-$3.19M

Top Buyers

1
Marshall Wace
Marshall Wace
United Kingdom
+$4.93M
2
Morgan Stanley
Morgan Stanley
New York
+$3.51M
3
Millennium Management
Millennium Management
New York
+$1.89M
4
Osaic Holdings
Osaic Holdings
Arizona
+$1.32M
5
State Street
State Street
Massachusetts
+$1.19M

Top Sellers

1
CAM
Cormorant Asset Management
Massachusetts
-$2.96M
2
UBS Group
UBS Group
Switzerland
-$1.55M
3
SFI
Susquehanna Fundamental Investments
Pennsylvania
-$1.12M
4
BCM
Bridgeway Capital Management
Texas
-$1.01M
5
SC
Sculptor Capital
New York
-$929K
Name Holding Trade Value Shares
Change 		Shares
Change %
Ameriprise
26
Ameriprise
Minnesota
$990K -$132 -16 -0%
NL
27
Nuveen LLC
North Carolina
$938K +$938K +114,057 New
Bank of America
28
Bank of America
North Carolina
$922K -$58.1K -7,064 -6%
RhumbLine Advisers
29
RhumbLine Advisers
Massachusetts
$884K -$5.15K -626 -0.6%
Two Sigma Investments
30
Two Sigma Investments
New York
$868K -$471K -57,352 -35%
Invesco
31
Invesco
Georgia
$716K +$450K +54,696 +169%
Jacobs Levy Equity Management
32
Jacobs Levy Equity Management
New Jersey
$703K -$156K -19,024 -18%
Barclays
33
Barclays
United Kingdom
$669K -$184K -22,385 -22%
T. Rowe Price Associates
34
T. Rowe Price Associates
Maryland
$621K +$295K +35,922 +91%
Wealth Enhancement Advisory Services
35
Wealth Enhancement Advisory Services
Minnesota
$579K +$579K +70,398 New
AFG
36
American Financial Group
Ohio
$527K – – –
Simplex Trading
37
Simplex Trading
Illinois
$521K -$338K -41,141 -39%
MWM
38
Mindset Wealth Management
Indiana
$518K – – –
HighTower Advisors
39
HighTower Advisors
Illinois
$496K +$8.22K +1,000 +2%
AllianceBernstein
40
AllianceBernstein
Tennessee
$419K – – –
Citigroup
41
Citigroup
New York
$412K +$48.8K +5,939 +13%
Wells Fargo
42
Wells Fargo
California
$380K +$107K +13,058 +39%
Acadian Asset Management
43
Acadian Asset Management
Massachusetts
$357K +$357K +43,695 New
Franklin Resources
44
Franklin Resources
California
$350K +$242K +29,391 +223%
Deutsche Bank
45
Deutsche Bank
Germany
$345K +$16.2K +1,973 +5%
GCM
46
Graham Capital Management
Connecticut
$323K +$323K +39,327 New
JPMorgan Chase & Co
47
JPMorgan Chase & Co
New York
$294K +$29.9K +3,642 +11%
Comerica Bank
48
Comerica Bank
Texas
$288K – – –
CCG
49
Cypress Capital Group
Florida
$286K – – –
AQR Capital Management
50
AQR Capital Management
Connecticut
$285K -$36.9K -4,492 -11%
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