|
1
|
Deerfield Management
New York
|
$1.74B
|
-$73.2M
|
-742,574
|
-4%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$1.09B
|
+$82.8M
|
+839,647
|
+8%
|
|
|
3
|
Paradigm Biocapital Advisors
New York
|
$530M
|
–
|
–
|
–
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$528M
|
+$63M
|
+639,264
|
+14%
|
|
|
5
|
|
$483M
|
+$70.9M
|
+719,466
|
+18%
|
|
|
6
|
Wellington Management Group
Boston,
Massachusetts
|
$248M
|
+$15.9M
|
+160,958
|
+7%
|
|
|
7
|
|
$222M
|
+$52.4M
|
+531,242
|
+32%
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$216M
|
+$33.2M
|
+336,518
|
+19%
|
|
|
9
|
RA Capital Management
Boston,
Massachusetts
|
$189M
|
+$62.5M
|
+633,601
|
+51%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$188M
|
+$28.6M
|
+289,928
|
+18%
|
|
|
11
|
Perceptive Advisors
New York
|
$167M
|
+$10.1M
|
+102,769
|
+7%
|
|
|
12
|
Polar Capital Holdings
London,
United Kingdom
|
$155M
|
+$50.7M
|
+514,634
|
+50%
|
|
|
13
|
Janus Henderson Group
London,
|
$151M
|
-$67.9M
|
-689,100
|
-31%
|
|
|
14
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$133M
|
+$29.5M
|
+298,727
|
+29%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$125M
|
+$14.2M
|
+144,241
|
+13%
|
|
|
16
|
Bellevue Group
Kuesnacht,
Switzerland
|
$104M
|
+$102M
|
+1,037,468
|
New
|
|
|
17
|
Braidwell
Stamford,
Connecticut
|
$82.6M
|
-$18.9M
|
-191,576
|
-19%
|
|
|
18
|
AllianceBernstein
Nashville,
Tennessee
|
$79M
|
+$72.5M
|
+735,477
|
+1,472%
|
|
|
19
|
Fairmount Funds Management
West Conshohocken,
Pennsylvania
|
$73.2M
|
–
|
–
|
–
|
|
|
20
|
Adage Capital Partners
Boston,
Massachusetts
|
$64.7M
|
+$6.75M
|
+68,500
|
+12%
|
|
|
21
|
Woodline Partners
San Francisco,
California
|
$61.4M
|
-$45.3M
|
-459,061
|
-43%
|
|
|
22
|
|
$59.8M
|
+$14.8M
|
+150,023
|
+34%
|
|
|
23
|
|
$57.8M
|
+$56.6M
|
+574,242
|
New
|
|
|
24
|
Ameriprise
Minneapolis,
Minnesota
|
$56.8M
|
+$3.67M
|
+37,248
|
+7%
|
|
|
25
|
Commodore Capital
New York
|
$55.3M
|
-$83.8M
|
-850,000
|
-61%
|
|
