|
1
|
Deerfield Management
New York
|
$1.41B
|
-$187M
|
-2,000,000
|
-10%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$756M
|
-$2.43K
|
-26
|
-0%
|
|
|
3
|
Paradigm Biocapital Advisors
New York
|
$420M
|
+$33.9M
|
+363,379
|
+7%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$352M
|
+$34.2M
|
+366,239
|
+9%
|
|
|
5
|
|
$302M
|
+$21.2M
|
+226,596
|
+6%
|
|
|
6
|
Perceptive Advisors
New York
|
$205M
|
-$33.5M
|
-359,258
|
-12%
|
|
|
7
|
Commodore Capital
New York
|
$127M
|
+$63.7M
|
+681,600
|
+73%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$117M
|
+$23M
|
+246,581
|
+20%
|
|
|
9
|
Bain Capital Life Sciences Investors
Boston,
Massachusetts
|
$113M
|
-$117M
|
-1,250,000
|
-46%
|
|
|
10
|
Fairmount Funds Management
West Conshohocken,
Pennsylvania
|
$103M
|
-$34.5M
|
-369,400
|
-22%
|
|
|
11
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$102M
|
+$20.1M
|
+215,633
|
+20%
|
|
|
12
|
Wellington Management Group
Boston,
Massachusetts
|
$101M
|
+$25.5M
|
+272,738
|
+27%
|
|
|
13
|
Woodline Partners
San Francisco,
California
|
$94.3M
|
+$1.05M
|
+11,248
|
+0.9%
|
|
|
14
|
Boxer Capital Management
San Diego,
California
|
$87.7M
|
+$105M
|
+1,120,192
|
New
|
|
|
15
|
Polar Capital Holdings
London,
United Kingdom
|
$74.1M
|
+$54.6M
|
+584,223
|
+161%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$68.2M
|
+$1.48M
|
+15,878
|
+2%
|
|
|
17
|
Driehaus Capital Management
Chicago,
Illinois
|
$62.1M
|
-$6.59M
|
-70,541
|
-8%
|
|
|
18
|
Adage Capital Partners
Boston,
Massachusetts
|
$53.2M
|
+$37.4M
|
+400,000
|
+143%
|
|
|
19
|
Pictet Asset Management
Carouge,
Switzerland
|
$50.2M
|
+$1.93M
|
+20,648
|
+3%
|
|
|
20
|
Vestal Point Capital
New York
|
$47M
|
+$56M
|
+600,000
|
New
|
|
|
21
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$33.7M
|
–
|
–
|
–
|
|
|
22
|
Silverarc Capital Management
Boston,
Massachusetts
|
$31.3M
|
+$2.67M
|
+28,573
|
+8%
|
|
|
23
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$28.8M
|
+$4.64M
|
+49,728
|
+16%
|
|
|
24
|
Marshall Wace
London,
United Kingdom
|
$28.3M
|
+$20.5M
|
+219,336
|
+155%
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$26.3M
|
+$1.47M
|
+15,770
|
+5%
|
|