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Nautilus Biotechnolgy
NAUT

81 hedge funds and large institutions have $211M invested in Nautilus Biotechnolgy in 2026 Q1 according to their latest regulatory filings, with 25 funds opening new positions, 16 increasing their positions, 16 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed

178% more first-time investments, than exits

New positions opened: 25 | Existing positions closed: 9

85% more capital invested

Capital invested by funds: $114M → $211M (+$96.9M)

19% more funds holding

Funds holding: 68 → 81 (+13)

0% more repeat investments, than reductions

Existing positions increased: 16 | Existing positions reduced: 16

3.31% less ownership

Funds ownership: 46.25% → 42.94% (-3.3%)

33% less funds holding in top 10

Funds holding in top 10: 3 → 2 (-1)

Holders
81
Holders Change
+13
Holders Change %
+19.12%
% of All Funds
1%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.02%
New
25
Increased
16
Reduced
16
Closed
9
Calls
$261K
Puts
–
Net Calls
+$261K
Net Calls Change
+$257K

Top Buyers

1
CA
Clearstead Advisors
Ohio
+$5.72M
2
Millennium Management
Millennium Management
New York
+$623K
3
Marshall Wace
Marshall Wace
United Kingdom
+$498K
4
Acadian Asset Management
Acadian Asset Management
Massachusetts
+$318K
5
CAM
Crown Advisors Management
California
+$246K

Top Sellers

1
Alyeska Investment Group
Alyeska Investment Group
Illinois
-$494K
2
Jane Street
Jane Street
New York
-$356K
3
Corient Private Wealth
Corient Private Wealth
Florida
-$282K
4
OAC
OMERS Administration Corp
Ontario, Canada
-$197K
5
GCP
GSA Capital Partners
United Kingdom
-$170K
Name Holding Trade Value Shares
Change 		Change in
Stake
ACM
1
AH Capital Management
California
$68.5M – – –
PA
2
Perceptive Advisors
New York
$48.9M – – –
CM
3
Cercano Management
Washington
$27.8M – – –
VCM
4
Vanguard Capital Management
Pennsylvania
$9.88M +$6.26M +2,545,597 New
CA
5
Clearstead Advisors
Ohio
$9.04M +$5.72M +2,329,784 New
CFM
6
Comprehensive Financial Management
California
$8.57M – – –
ACI
7
Amazon.com Inc
Washington
$5.65M – – –
Millennium Management
8
Millennium Management
New York
$4.94M +$623K +253,387 +25%
ST
9
Sentinel Trust
Texas
$2.91M – – –
Acadian Asset Management
10
Acadian Asset Management
Massachusetts
$2.87M +$318K +129,262 +21%
TM
11
Tikvah Management
North Carolina
$2.82M – – –
Geode Capital Management
12
Geode Capital Management
Massachusetts
$2.34M +$105K +42,615 +8%
Goldman Sachs
13
Goldman Sachs
New York
$1.52M +$229K +93,331 +31%
Dimensional Fund Advisors
14
Dimensional Fund Advisors
Texas
$1.27M +$107K +43,684 +15%
Marshall Wace
15
Marshall Wace
United Kingdom
$1.24M +$498K +202,823 +173%
VFT
16
Vanguard Fiduciary Trust
Pennsylvania
$1.19M +$751K +305,526 New
Renaissance Technologies
17
Renaissance Technologies
New York
$1.03M +$14.3K +5,800 +2%
State Street
18
State Street
Massachusetts
$839K +$36.9K +15,015 +7%
HC
19
Hillman Company
Pennsylvania
$776K – – –
BlackRock
20
BlackRock
New York
$728K -$4.33K -1,760 -0.9%
CA
21
Crewe Advisors
Utah
$528K – – –
BCM
22
Bridgeway Capital Management
Texas
$504K – – –
Corient Private Wealth
23
Corient Private Wealth
Florida
$445K -$282K -114,788 -50%
Northern Trust
24
Northern Trust
Illinois
$415K – – –
CAM
25
Crown Advisors Management
California
$388K +$246K +100,000 New
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