|
1
|
Catalys Pacific
Tokyo,
Japan
|
$287M
|
-$40.1M
|
-1,000,000
|
-11%
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$266M
|
–
|
–
|
–
|
|
|
3
|
Samsara BioCapital
Palo Alto,
California
|
$213M
|
-$15.7M
|
-392,133
|
-6%
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$184M
|
+$120M
|
+2,986,254
|
+144%
|
|
|
5
|
|
$157M
|
+$26.3M
|
+656,064
|
+18%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$122M
|
+$13.4M
|
+333,881
|
+11%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$116M
|
+$75.5M
|
+1,881,976
|
+144%
|
|
|
8
|
Caligan Partners
New York
|
$101M
|
–
|
–
|
–
|
|
|
9
|
Franklin Resources
San Mateo,
California
|
$64.9M
|
-$843K
|
-21,021
|
-1%
|
|
|
10
|
Laurion Capital Management
New York
|
$62.2M
|
-$279K
|
-6,960
|
-0.4%
|
|
|
11
|
Holocene Advisors
New York
|
$58.1M
|
+$15.9M
|
+396,658
|
+33%
|
|
|
12
|
|
$57.8M
|
+$63.8M
|
+1,591,917
|
New
|
|
|
13
|
SR One Capital Management
Wayne,
Pennsylvania
|
$56.8M
|
-$22.1M
|
-549,967
|
-26%
|
|
|
14
|
Suvretta Capital Management
New York
|
$55.8M
|
-$23.8M
|
-593,471
|
-28%
|
|
|
15
|
|
$52.7M
|
+$29.6M
|
+739,272
|
+104%
|
|
|
16
|
Polar Capital Holdings
London,
United Kingdom
|
$50.8M
|
+$13.7M
|
+342,365
|
+32%
|
|
|
17
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$48.1M
|
+$52.3M
|
+1,303,737
|
+6,097%
|
|
|
18
|
|
$47.4M
|
+$52.3M
|
+1,304,932
|
New
|
|
|
19
|
Jennison Associates
New York
|
$45.7M
|
+$35.4M
|
+882,307
|
+234%
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$45.6M
|
+$5.38M
|
+134,171
|
+12%
|
|
|
21
|
Janus Henderson Group
London,
|
$44M
|
+$47.9M
|
+1,193,417
|
+6,013%
|
|
|
22
|
Point72 Asset Management
Stamford,
Connecticut
|
$43.8M
|
-$23.8M
|
-592,408
|
-33%
|
|
|
23
|
Capital International Investors
Los Angeles,
California
|
$42.2M
|
-$49.3M
|
-1,230,106
|
-51%
|
|
|
24
|
|
$41.8M
|
+$21.6M
|
+539,747
|
+88%
|
|
|
25
|
Boothbay Fund Management
New York
|
$36M
|
+$1.98M
|
+49,456
|
+5%
|
|
