|
1
|
Catalys Pacific
Tokyo,
Japan
|
$338M
|
–
|
–
|
–
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$278M
|
+$25.4M
|
+1,176,470
|
+19%
|
|
|
3
|
Samsara BioCapital
Palo Alto,
California
|
$237M
|
+$12.7M
|
+588,235
|
+10%
|
|
|
4
|
|
$139M
|
+$12.4M
|
+573,854
|
+19%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$114M
|
+$15M
|
+692,550
|
+30%
|
|
|
6
|
Caligan Partners
New York
|
$105M
|
+$16.3M
|
+755,302
|
+37%
|
|
|
7
|
Capital International Investors
Los Angeles,
California
|
$90.8M
|
-$10.9M
|
-505,624
|
-17%
|
|
|
8
|
Suvretta Capital Management
New York
|
$80.9M
|
+$8.38M
|
+387,641
|
+22%
|
|
|
9
|
SR One Capital Management
Wayne,
Pennsylvania
|
$80.2M
|
-$21.9M
|
-1,014,000
|
-32%
|
|
|
10
|
Fidelity Investments
Boston,
Massachusetts
|
$78.5M
|
+$38.2M
|
+1,766,369
|
+579%
|
|
|
11
|
Citadel Advisors
Miami,
Florida
|
$78.4M
|
+$44.4M
|
+2,052,845
|
+14,274%
|
|
|
12
|
Franklin Resources
San Mateo,
California
|
$68.6M
|
+$133K
|
+6,171
|
+0.3%
|
|
|
13
|
Point72 Asset Management
Stamford,
Connecticut
|
$68.2M
|
+$38.9M
|
+1,799,628
|
New
|
|
|
14
|
Laurion Capital Management
New York
|
$65.2M
|
-$911K
|
-42,137
|
-2%
|
|
|
15
|
Farallon Capital Management
San Francisco,
California
|
$63.4M
|
+$36.2M
|
+1,673,053
|
New
|
|
|
16
|
Integral Health Asset Management
New York
|
$56.9M
|
-$26M
|
-1,200,000
|
-44%
|
|
|
17
|
|
$55.7M
|
+$15.3M
|
+709,143
|
+93%
|
|
|
18
|
|
$52.2M
|
+$17.1M
|
+789,168
|
+134%
|
|
|
19
|
State Street
Boston,
Massachusetts
|
$49.4M
|
-$3.04M
|
-140,536
|
-10%
|
|
|
20
|
Holocene Advisors
New York
|
$45.7M
|
+$26.1M
|
+1,205,377
|
New
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$42.6M
|
+$3.65M
|
+168,851
|
+18%
|
|
|
22
|
Polar Capital Holdings
London,
United Kingdom
|
$40.1M
|
+$22.9M
|
+1,058,776
|
New
|
|
|
23
|
Boothbay Fund Management
New York
|
$35.7M
|
+$2.72M
|
+125,700
|
+15%
|
|
|
24
|
Pictet Asset Management
Carouge,
Switzerland
|
$35.2M
|
-$7.33M
|
-338,824
|
-27%
|
|
|
25
|
AllianceBernstein
Nashville,
Tennessee
|
$33.5M
|
+$18.5M
|
+855,348
|
+3,160%
|
|
