|
1
|
Catalys Pacific
Tokyo,
Japan
|
$213M
|
–
|
–
|
–
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$208M
|
–
|
–
|
–
|
|
|
3
|
|
$159M
|
+$38.6M
|
+1,405,456
|
+31%
|
|
|
4
|
Samsara BioCapital
Palo Alto,
California
|
$158M
|
–
|
–
|
–
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$122M
|
-$9.6M
|
-349,415
|
-7%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$112M
|
+$33.1M
|
+1,205,696
|
+41%
|
|
|
7
|
Deerfield Management
New York
|
$107M
|
+$109M
|
+3,958,000
|
New
|
|
|
8
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$74.4M
|
+$8.3M
|
+302,407
|
+12%
|
|
|
9
|
Laurion Capital Management
New York
|
$67.6M
|
+$7.52M
|
+274,112
|
+12%
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$61M
|
+$25.2M
|
+919,163
|
+68%
|
|
|
11
|
|
$56.9M
|
+$1.57M
|
+57,400
|
+3%
|
|
|
12
|
Capital World Investors
Los Angeles,
California
|
$53.9M
|
+$43.9M
|
+1,599,428
|
+402%
|
|
|
13
|
Armistice Capital
New York
|
$46.8M
|
+$15.4M
|
+560,000
|
+48%
|
|
|
14
|
Troluce Capital Advisors
Dorado,
Puerto Rico
|
$46.6M
|
+$29.5M
|
+1,073,753
|
+164%
|
|
|
15
|
Franklin Resources
San Mateo,
California
|
$44.1M
|
-$4.09M
|
-149,142
|
-8%
|
|
|
16
|
|
$42.9M
|
–
|
–
|
–
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$42.8M
|
+$7.77M
|
+283,191
|
+22%
|
|
|
18
|
SR One Capital Management
Wayne,
Pennsylvania
|
$42.2M
|
–
|
–
|
–
|
|
|
19
|
Bank of America
Charlotte,
North Carolina
|
$40.6M
|
+$11.1M
|
+405,175
|
+37%
|
|
|
20
|
Sphera Funds Management
Tel Aviv,
Israel
|
$39.7M
|
+$3.57M
|
+130,000
|
+10%
|
|
|
21
|
|
$39.4M
|
+$18.5M
|
+673,633
|
+86%
|
|
|
22
|
Pictet Asset Management
Carouge,
Switzerland
|
$38.6M
|
+$10.9M
|
+396,211
|
+38%
|
|
|
23
|
Polar Capital Holdings
London,
United Kingdom
|
$38.3M
|
-$2.19M
|
-79,895
|
-5%
|
|
|
24
|
Millennium Management
New York
|
$33M
|
+$19.1M
|
+696,498
|
+133%
|
|
|
25
|
Ghisallo Capital Management
Boston,
Massachusetts
|
$30.4M
|
+$30.9M
|
+1,125,000
|
New
|
|
