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Mineralys Therapeutics

224 hedge funds and large institutions have $2.69B invested in Mineralys Therapeutics in 2026 Q2 according to their latest regulatory filings, with 36 funds opening new positions, 88 increasing their positions, 65 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

64% more first-time investments, than exits

New positions opened: 36 | Existing positions closed: 22

41% more call options, than puts

Call options by funds: $46.4M | Put options by funds: $33M

35% more repeat investments, than reductions

Existing positions increased: 88 | Existing positions reduced: 65

11.11% more ownership

Funds ownership: 109.62%120.72% (+11%)

9% more capital invested

Capital invested by funds: $2.46B → $2.69B (+$232M)

5% more funds holding

Funds holding: 214224 (+10)

10% less funds holding in top 10

Funds holding in top 10: 109 (-1)

Holders
224
Holders Change
+10
Holders Change %
+4.67%
% of All Funds
2.71%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.11%
New
36
Increased
88
Reduced
65
Closed
22
Calls
$46.4M
Puts
$33M
Net Calls
+$13.4M
Net Calls Change
+$17.8M
Name Holding Trade Value Shares
Change
Change in
Stake
CP
1
Catalys Pacific
Japan
$213M
RCM
2
RA Capital Management
Massachusetts
$208M
BlackRock
3
BlackRock
New York
$159M +$38.6M +1,405,456 +31%
SB
4
Samsara BioCapital
California
$158M
Fidelity Investments
5
Fidelity Investments
Massachusetts
$122M -$9.59M -349,415 -7%
State Street
6
State Street
Massachusetts
$112M +$33.1M +1,205,696 +41%
DM
7
Deerfield Management
New York
$107M +$109M +3,958,000 New
Vanguard Capital Management
8
Vanguard Capital Management
Pennsylvania
$74.4M +$8.3M +302,407 +12%
LCM
9
Laurion Capital Management
New York
$67.6M +$7.52M +274,112 +12%
T. Rowe Price Associates
10
T. Rowe Price Associates
Maryland
$61M +$25.2M +919,163 +68%
O
11
OrbiMed
New York
$56.9M +$1.57M +57,400 +3%
Capital World Investors
12
Capital World Investors
California
$53.9M +$43.9M +1,599,428 +402%
AC
13
Armistice Capital
New York
$46.8M +$15.4M +560,000 +48%
TCA
14
Troluce Capital Advisors
Puerto Rico
$46.6M +$29.5M +1,073,753 +164%
Franklin Resources
15
Franklin Resources
California
$44.1M -$4.09M -149,142 -8%
AP
16
Andera Partners
$42.9M
Geode Capital Management
17
Geode Capital Management
Massachusetts
$42.8M +$7.77M +283,191 +22%
SOCM
18
SR One Capital Management
Pennsylvania
$42.2M
Bank of America
19
Bank of America
North Carolina
$40.6M +$11.1M +405,175 +37%
SFM
20
Sphera Funds Management
Israel
$39.7M +$3.57M +130,000 +10%
Goldman Sachs
21
Goldman Sachs
New York
$39.4M +$18.5M +673,633 +86%
Pictet Asset Management
22
Pictet Asset Management
Switzerland
$38.6M +$10.9M +396,211 +38%
PCH
23
Polar Capital Holdings
United Kingdom
$38.3M -$2.19M -79,895 -5%
Millennium Management
24
Millennium Management
New York
$33M +$19.1M +696,498 +133%
GCM
25
Ghisallo Capital Management
Massachusetts
$30.4M +$30.9M +1,125,000 New

MLYS Hedge Fund Activity: Q2 2026 in Review

224 of the 8,274 institutional investors tracked by Wall St. Rank reported a position in Mineralys Therapeutics (MLYS) for Q2 2026, worth a combined $2.69B — up 9.5% from $2.46B a quarter earlier.

Buyers outnumbered sellers: 36 funds opened new MLYS positions and 22 closed out — a net gain of 14 holders — while 88 added to existing stakes and 65 trimmed.

The largest buyer was Deerfield Management, opening a new position worth an estimated $109M. The largest seller was Caligan Partners, exiting entirely with an estimated $75.1M sold.

  • 224 institutional investors held Mineralys Therapeutics (MLYS) as of Q2 2026, up from 214 in Q1 2026.
  • Funds reported $2.69B of Mineralys Therapeutics stock for Q2 2026, up 9.5% quarter-over-quarter.
  • 36 funds opened new Mineralys Therapeutics positions in Q2 2026 and 22 closed out, a net change of +14 holders.
  • The largest Mineralys Therapeutics buyer in Q2 2026 was Deerfield Management, an estimated $109M added.
  • The largest Mineralys Therapeutics seller in Q2 2026 was Caligan Partners, an estimated $75.1M sold.

Based on aggregated 13F filings for Q2 2026.