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Mineralys Therapeutics

165 hedge funds and large institutions have $889M invested in Mineralys Therapeutics in 2025 Q2 according to their latest regulatory filings, with 41 funds opening new positions, 76 increasing their positions, 30 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

153% more repeat investments, than reductions

Existing positions increased: 76 | Existing positions reduced: 30

71% more first-time investments, than exits

New positions opened: 41 | Existing positions closed: 24

11% more funds holding

Funds holding: 149165 (+16)

3.37% more ownership

Funds ownership: 97.42%100.79% (+3.4%)

9% less capital invested

Capital invested by funds: $971M → $889M (-$82.6M)

10% less funds holding in top 10

Funds holding in top 10: 109 (-1)

97% less call options, than puts

Call options by funds: $30K | Put options by funds: $1.11M

Holders
165
Holders Change
+16
Holders Change %
+10.74%
% of All Funds
2.17%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
41
Increased
76
Reduced
30
Closed
24
Calls
$30K
Puts
$1.11M
Net Calls
-$1.08M
Net Calls Change
+$2.81M
Name Holding Trade Value Shares
Change
Change in
Stake
CP
1
Catalys Pacific
Japan
$120M
RCM
2
RA Capital Management
Massachusetts
$83.2M
SB
3
Samsara BioCapital
California
$76.8M
SOCM
4
SR One Capital Management
Pennsylvania
$42.3M
BlackRock
5
BlackRock
New York
$41.9M +$9.39M +647,733 +26%
Capital International Investors
6
Capital International Investors
California
$39.2M +$42M +2,899,020 New
IHAM
7
Integral Health Asset Management
New York
$36.5M +$5.8M +400,000 +17%
Vanguard Group
8
Vanguard Group
Pennsylvania
$31.5M +$4.22M +290,943 +14%
CP
9
Caligan Partners
New York
$27.3M -$1.92M -132,315 -6%
Franklin Resources
10
Franklin Resources
California
$24.4M +$341K +23,556 +1%
LCM
11
Laurion Capital Management
New York
$23.8M -$1.97M -135,602 -7%
SCM
12
Suvretta Capital Management
New York
$23.6M +$1.11M +76,733 +5%
State Street
13
State Street
Massachusetts
$19.5M +$13.4M +923,379 +178%
Pictet Asset Management
14
Pictet Asset Management
Switzerland
$17.2M +$777K +53,620 +4%
Jennison Associates
15
Jennison Associates
New York
$16.7M -$10.8M -743,711 -38%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$12.9M +$2.21M +152,560 +19%
AAA
17
Affinity Asset Advisors
New York
$12.2M -$2.9M -200,000 -18%
American Century Companies
18
American Century Companies
Missouri
$11.3M +$162K +11,165 +1%
CS
19
Candriam SCA
Luxembourg
$11.2M -$850K -58,646 -7%
BFM
20
Boothbay Fund Management
New York
$11.1M -$1.54M -106,477 -12%
O
21
OrbiMed
New York
$10.3M +$11M +760,351 New
SC
22
Stempoint Capital
New York
$8.55M +$9.15M +631,586 New
Goldman Sachs
23
Goldman Sachs
New York
$8.48M +$4.76M +328,392 +110%
Morgan Stanley
24
Morgan Stanley
New York
$7.95M -$463K -31,918 -5%
D.E. Shaw & Co
25
D.E. Shaw & Co
New York
$7.77M +$1.39M +95,777 +20%

MLYS Hedge Fund Activity: Q2 2025 in Review

165 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Mineralys Therapeutics (MLYS) for Q2 2025, worth a combined $889M — down 8.5% from $971M a quarter earlier.

Buyers outnumbered sellers: 41 funds opened new MLYS positions and 24 closed out — a net gain of 17 holders — while 76 added to existing stakes and 30 trimmed.

The largest buyer was Capital International Investors, opening a new position worth an estimated $42M. The largest seller was TCG Crossover Management, exiting entirely with an estimated $39.2M sold.

  • 165 institutional investors held Mineralys Therapeutics (MLYS) as of Q2 2025, up from 149 in Q1 2025.
  • Funds reported $889M of Mineralys Therapeutics stock for Q2 2025, down 8.5% quarter-over-quarter.
  • 41 funds opened new Mineralys Therapeutics positions in Q2 2025 and 24 closed out, a net change of +17 holders.
  • The largest Mineralys Therapeutics buyer in Q2 2025 was Capital International Investors, an estimated $42M added.
  • The largest Mineralys Therapeutics seller in Q2 2025 was TCG Crossover Management, an estimated $39.2M sold.

Based on aggregated 13F filings for Q2 2025.