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Mirum Pharmaceuticals

214 hedge funds and large institutions have $2.82B invested in Mirum Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 35 funds opening new positions, 76 increasing their positions, 80 reducing their positions, and 33 closing their positions.

New
Increased
Maintained
Reduced
Closed

15% more capital invested

Capital invested by funds: $2.44B → $2.82B (+$375M)

1.35% more ownership

Funds ownership: 110.47%111.83% (+1.4%)

6% more first-time investments, than exits

New positions opened: 35 | Existing positions closed: 33

0% more funds holding

Funds holding: 214214 (0)

5% less repeat investments, than reductions

Existing positions increased: 76 | Existing positions reduced: 80

18% less funds holding in top 10

Funds holding in top 10: 119 (-2)

69% less call options, than puts

Call options by funds: $1.55M | Put options by funds: $5.06M

Holders
214
Holders Change
Holders Change %
0%
% of All Funds
2.82%
Holding in Top 10
9
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-18.18%
% of All Funds
0.12%
New
35
Increased
76
Reduced
80
Closed
33
Calls
$1.55M
Puts
$5.06M
Net Calls
-$3.51M
Net Calls Change
-$1.16M
Name Holding Trade Value Shares
Change
Change in
Stake
FLSM
1
Frazier Life Sciences Management
California
$346M
Janus Henderson Group
2
Janus Henderson Group
United Kingdom
$266M +$20.9M +470,168 +10%
BlackRock
3
BlackRock
New York
$182M +$10.6M +237,534 +7%
BI
4
BVF Inc
California
$141M -$1.57M -35,180 -1%
EAM
5
Eventide Asset Management
Massachusetts
$134M +$4.92M +110,485 +4%
Vanguard Group
6
Vanguard Group
Pennsylvania
$131M +$1.1M +24,808 +1%
NHAS
7
Novo Holdings A/S
Denmark
$76.3M +$2.45K +55 +0%
T. Rowe Price Associates
8
T. Rowe Price Associates
Maryland
$72.1M +$92.5K +2,078 +0.1%
Citadel Advisors
9
Citadel Advisors
Florida
$71.6M -$1.77M -39,643 -3%
State Street
10
State Street
Massachusetts
$70M -$5.3M -118,938 -8%
TCM
11
Tang Capital Management
California
$62.9M -$48.1K -1,080 -0.1%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$52.4M +$2.94M +65,951 +7%
ClearBridge Investments
13
ClearBridge Investments
New York
$52.3M +$2.2M +49,460 +5%
PCH
14
Polar Capital Holdings
United Kingdom
$49.6M -$8.9M -200,000 -17%
RSCM
15
Rock Springs Capital Management
Maryland
$41.6M -$5.95M -133,559 -14%
Lord, Abbett & Co
16
Lord, Abbett & Co
New Jersey
$39.2M -$1.88M -42,252 -5%
Pictet Asset Management
17
Pictet Asset Management
Switzerland
$35.7M -$3.43M -77,088 -10%
BCM
18
Boone Capital Management
Georgia
$32.6M +$1.7M +38,130 +6%
Franklin Resources
19
Franklin Resources
California
$30.2M +$10.7K +241 +0%
N
20
Nuveen
North Carolina
$30M -$2.87M -64,465 -10%
WP
21
Woodline Partners
California
$28.9M +$72.3K +1,623 +0.3%
Morgan Stanley
22
Morgan Stanley
New York
$28.8M -$1.79M -40,105 -7%
D.E. Shaw & Co
23
D.E. Shaw & Co
New York
$28.2M +$520K +11,680 +2%
Loomis, Sayles & Company
24
Loomis, Sayles & Company
Massachusetts
$28.1M -$588K -13,198 -2%
FTM
25
First Turn Management
California
$26.8M +$1.09M +24,526 +5%

MIRM Hedge Fund Activity: Q2 2025 in Review

214 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Mirum Pharmaceuticals (MIRM) for Q2 2025, worth a combined $2.82B — up 15% from $2.44B a quarter earlier.

Buyers outnumbered sellers: 35 funds opened new MIRM positions and 33 closed out — a net gain of 2 holders — while 76 added to existing stakes and 80 trimmed.

The largest buyer was Janus Henderson Group, adding an estimated $20.9M. The largest seller was Invesco, cutting an estimated $11.1M.

  • 214 institutional investors held Mirum Pharmaceuticals (MIRM) as of Q2 2025, unchanged from Q1 2025.
  • Funds reported $2.82B of Mirum Pharmaceuticals stock for Q2 2025, up 15% quarter-over-quarter.
  • 35 funds opened new Mirum Pharmaceuticals positions in Q2 2025 and 33 closed out, a net change of +2 holders.
  • The largest Mirum Pharmaceuticals buyer in Q2 2025 was Janus Henderson Group, an estimated $20.9M added.
  • The largest Mirum Pharmaceuticals seller in Q2 2025 was Invesco, an estimated $11.1M sold.

Based on aggregated 13F filings for Q2 2025.