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Madrigal Pharmaceuticals

303 hedge funds and large institutions have $7.13B invested in Madrigal Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 40 funds opening new positions, 105 increasing their positions, 109 reducing their positions, and 51 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more funds holding in top 10

Funds holding in top 10:

less ownership

Funds ownership:

less repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

4% less funds holding

Funds holding: 317303 (-14)

9% less capital invested

Capital invested by funds: $7.82B → $7.13B (-$690M)

22% less first-time investments, than exits

New positions opened: 40 | Existing positions closed: 51

Holders
303
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
12
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$294M
Puts
$155M
Net Calls
Net Calls Change

Top Buyers

1 +$62.5M
2 +$56.6M
3 +$55.9M
4
UBS Group
UBS Group
Switzerland
+$55.7M
5
PCH
Polar Capital Holdings
United Kingdom
+$22.8M

Top Sellers

1 -$129M
2 -$62.6M
3 -$47.8M
4
ACA
Avoro Capital Advisors
New York
-$44.6M
5
Morgan Stanley
Morgan Stanley
New York
-$41.4M
Name Holding Trade Value Shares
Change
Change in
Stake
XT
201
XTX Topco
Cayman Islands
$375K
BHCM
202
Brevan Howard Capital Management
Jersey
$353K
AI
203
Atria Investments
North Carolina
$347K
Cerity Partners
204
Cerity Partners
New York
$343K
Osaic Holdings
205
Osaic Holdings
Arizona
$341K
OAM
206
Oppenheimer Asset Management
New York
$339K
BG
207
Bellevue Group
Switzerland
$333K
ACM
208
ADAR1 Capital Management
Texas
$319K
RF
209
Rossby Financial
Florida
$317K
HSBC Holdings
210
HSBC Holdings
United Kingdom
$309K
William Blair & Company
211
William Blair & Company
Illinois
$303K
VPIM
212
Vanguard Personalized Indexing Management
California
$298K
CPIG
213
Chicago Partners Investment Group
Illinois
$297K
Wolverine Trading
214
Wolverine Trading
Illinois
$292K
SC
215
Syon Capital
California
$291K
OMC
216
Overbrook Management Corp
New York
$259K
CGIM
217
Cannon Global Investment Management
Florida
$242K
P
218
Pitcairn
Pennsylvania
$241K
Comerica Bank
219
Comerica Bank
Texas
$229K
DWT
220
Dorsey & Whitney Trust
South Dakota
$228K
SAM
221
Sectoral Asset Management
Quebec, Canada
$221K
MMA
222
Miracle Mile Advisors
California
$213K
GCP
223
Garda Capital Partners
Minnesota
$212K
PAS
224
Park Avenue Securities
New York
$212K
QCM
225
QRG Capital Management
Illinois
$210K