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Madrigal Pharmaceuticals

387 hedge funds and large institutions have $13.7B invested in Madrigal Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 85 funds opening new positions, 137 increasing their positions, 113 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

107% more first-time investments, than exits

New positions opened: 85 | Existing positions closed: 41

28% more capital invested

Capital invested by funds: $10.7B → $13.7B (+$2.99B)

21% more repeat investments, than reductions

Existing positions increased: 137 | Existing positions reduced: 113

19% more call options, than puts

Call options by funds: $323M | Put options by funds: $271M

10% more funds holding

Funds holding: 352387 (+35)

1.57% less ownership

Funds ownership: 105.34%103.78% (-1.6%)

7% less funds holding in top 10

Funds holding in top 10: 1413 (-1)

Holders
387
Holders Change
+35
Holders Change %
+9.94%
% of All Funds
4.71%
Holding in Top 10
13
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-7.14%
% of All Funds
0.16%
New
85
Increased
137
Reduced
113
Closed
41
Calls
$323M
Puts
$271M
Net Calls
+$52.6M
Net Calls Change
-$16.2M
Name Holding Trade Value Shares
Change
Change in
Stake
PCM
176
Penn Capital Management
Pennsylvania
$1.72M +$1.48M +2,902 New
BG
177
Bellevue Group
Switzerland
$1.68M +$251K +491 +21%
TRSOTSOK
178
Teachers Retirement System of the State of Kentucky
Kentucky
$1.67M
DIA
179
Dana Investment Advisors
Wisconsin
$1.67M -$161K -315 -10%
HS
180
HighVista Strategies
Massachusetts
$1.65M -$357K -698 -20%
XT
181
XTX Topco
Cayman Islands
$1.64M +$1.44M +2,819 New
AAM
182
AMI Asset Management
California
$1.6M -$344K -674 -20%
AIM
183
Aigen Investment Management
New York
$1.54M +$1.06M +2,067 +353%
QCG
184
Quadrant Capital Group
Ohio
$1.52M
BAMCO Inc
185
BAMCO Inc
New York
$1.46M -$51.1K -100 -4%
SG
186
Strid Group
Pennsylvania
$1.46M
Mariner
187
Mariner
Kansas
$1.41M +$309K +605 +33%
Allianz Asset Management
188
Allianz Asset Management
Germany
$1.4M -$358K -700 -23%
Commonwealth Equity Services
189
Commonwealth Equity Services
Massachusetts
$1.36M -$69K -135 -5%
Stifel Financial
190
Stifel Financial
Missouri
$1.36M -$144K -282 -11%
JFG
191
Jefferies Financial Group
New York
$1.34M +$1.17M +2,300 New
II
192
Inspire Investing
Idaho
$1.31M +$1.15M +2,256 New
SCA
193
Snowden Capital Advisors
New York
$1.3M -$146K -285 -11%
GC
194
Guggenheim Capital
Illinois
$1.26M +$274K +536 +33%
Teacher Retirement System of Texas
195
Teacher Retirement System of Texas
Texas
$1.25M -$705K -1,380 -39%
DADC
196
D.A. Davidson & Co
Montana
$1.24M +$29.6K +58 +3%
DMKJ
197
David M. Knott Jr
$1.16M
TFA
198
Toth Financial Advisory
Virginia
$1.16M +$1.02M +2,000 New
FC
199
FORA Capital
Florida
$1.16M -$258K -506 -20%
IMRF
200
Illinois Municipal Retirement Fund
Illinois
$1.11M +$972K +1,903 New